your proxy card as soon as possible, so that your shares may be represented at the meeting. For specific instructions on how to vote your shares, please refer to the section entitled “General Proxy Information” in the proxy statement.
By Order of the Board of Directors, | |
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| William Chou, M.D, |
| President and Chief Executive Officer |
Philadelphia, Pennsylvania
April 14, 2021[●], 2023
Important Notice Regarding the Availability of Proxy Materials for the virtual Annual Meeting of Stockholders to be held on May 27, 2021:25, 2023: the Proxy Statement and our 20202022 Annual Report on Form 10-K are available at www.ProxyVote.com. You will need the control number included on your proxy card or voting instruction form, or included in the e-mail to you if you received the proxy materials by e-mail, as such number will be required in order for stockholders to gain access to the virtual meeting.
PASSAGE BIO, INC.
PROXY STATEMENT FOR 20212023 ANNUAL MEETING OF STOCKHOLDERS
TABLE OF CONTENTS
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PROPOSAL NO. 2 RATIFICATION OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM |
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| REPORT OF THE AUDIT COMMITTEE |
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SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT |
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| APPENDIX A | 38 |
PASSAGE BIO, INC.
One Commerce Square
2005 Market Street, 39th Floor
Philadelphia, PA 19103
PROXY STATEMENT FOR THE 20212023 ANNUAL MEETING OF STOCKHOLDERS
April 14, 2021[●], 2023
INFORMATION ABOUT SOLICITATION AND VOTING
The accompanying proxy is solicited on behalf of the Board of Directors of Passage Bio, Inc. (Passage Bio or the Company) for use at Passage Bio’s 20212023 Annual Meeting of Stockholders (Annual Meeting) to be held via a virtual meeting due to the public health and travel concerns our stockholders may have and recommendations that public health officials have issued and may issue in light of the coronavirus (COVID-19) pandemic.. You will be able to participate in the Annual Meeting and vote during the Annual Meeting via live webcast by visiting www.virtualshareholdermeeting.com/PASG2021PASG2023 on Thursday, May 27, 202125, 2023 at 4:30 p.m.10:00 a.m., Eastern Time, and any adjournment or postponement thereof. You will need the control number included on your proxy card or voting instruction form, or included in the e-mail to you if you received the proxy materials by e-mail, as such number will be required in order for stockholders to gain access to the virtual Annual Meeting.
We are making this proxy statement, the accompanying form of proxy and our Annual Report on Form 10-K for the year ended December 31, 20202022 first available to stockholders on or about April 14, 2021.[●], 2023. An electronic copy of this proxy statement and Annual Report on Form 10-K are available at https://investors.passagebio.com/financials-and-filings/sec- filings.sec-filings.
Internet Availability of Proxy Materials
Under rules adopted by the U.S. Securities and Exchange Commission (the “SEC”)SEC), we are furnishing proxy materials to our stockholders primarily via the internet, instead of mailing printed copies to each stockholder. On or about April 14, 2021,[●], 2023, we expect to send to our stockholders a Notice of Internet Availability containing instructions on how to access our proxy materials, including our proxy statement and our Annual Report on Form 10-K. The Notice of Internet Availability also provides instructions on how to vote through the internet or by telephone and includes instructions on how to receive paper copies of the proxy materials by mail or an electronic copy of the proxy materials by email.
This process is designed to reduce our environmental impact and lower the costs of printing and distributing our proxy materials without impacting our stockholders’ timely access to this important information. However, if you would prefer to receive printed proxy materials, please follow the instructions included in the Notice of Internet Availability.
GENERAL INFORMATION ABOUT THE MEETING
Purpose of the Annual Meeting
At the Annual Meeting, stockholders will act upon the proposals described in this proxy statement. In addition, we will consider any other matters that are properly presented for a vote at the meeting. We are not aware of any other matters to be submitted for consideration at the meeting. If any other matters are properly presented for a vote at the meeting, the persons named in the proxy, who are officers of the company, have the authority in their discretion to vote the shares represented by the proxy.
Record Date; Quorum
Only holders of record of common stock at the close of business on April 5, 2021,3, 2023, the record date, will be entitled to vote at the Annual Meeting. At the close of business on April 5, 2021, 53,977,4843, 2023, [●] shares of common stock were outstanding and entitled to vote.
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The holders of a majority of the voting power of the shares of stock entitled to vote at the Annual Meeting as of the record date must be present or represented by proxy at the Annual Meeting in order to hold the meeting and conduct business. This presence is called a quorum. Your shares are counted as present at the Annual Meeting if you are present and vote online at the virtual Annual Meeting or if you have properly submitted a proxy.
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Voting Rights; Required Vote
Each holder of shares of common stock is entitled to one vote for each share of common stock held as of the close of business on April 5, 2021,3, 2023, the record date. You may vote all shares owned by you at such date, including (1) shares held directly in your name as the stockholder of record and (2) shares held for you as the beneficial owner in street name through a broker, bank, trustee or other nominee. Dissenters’ rights are not applicable to any of the matters being voted on.
Stockholder of Record: Shares Registered in Your Name. If on April 5, 2021,3, 2023, your shares were registered directly in your name with our transfer agent, Computershare Trust Company, N.A., then you are considered the stockholder of record with respect to those shares. As a stockholder of record, you may vote at the Annual Meeting, or vote in advance through the internet or by telephone, or if you request to receive paper proxy materials by mail, by filling out and returning the proxy card.
Beneficial Owner: Shares Registered in the Name of a Broker or Nominee. If on April 5, 2021,3, 2023, your shares were held in an account with a brokerage firm, bank or other nominee, then you are the beneficial owner of the shares held in street name. As a beneficial owner, you have the right to direct your broker on how to vote the shares held in your account, and your broker has enclosed or provided voting instructions for you to use in directing it on how to vote your shares. Because the brokerage firm, bank or other nominee that holds your shares is the stockholder of record, if you wish to attend the Annual Meeting and vote your shares, you must obtain a valid proxy from the firm that holds your shares giving you the right to vote the shares at the Annual Meeting.
Each director will be elected by a plurality of the votes cast at the Annual Meeting. This means that the three individuals nominated for election to the Board of Directors at the Annual Meeting receiving the highest number of “FOR” votes will be elected. You may either vote “FOR” one, two or all of the nominees or “WITHHOLD” your vote with respect to one, two or all of the nominees. A “WITHHOLD” will have the same effect as an abstention. You may not cumulate votes in the election of directors. Approval of the ratification of the appointment of our independent registered public accounting firm will be obtained if the number of the votes cast “FOR” the proposal exceeds the number of votes “AGAINST” the proposal. The affirmative vote of the holders of a majority of the votes castvoting power of all the outstanding shares of our capital stock entitled to vote at the Annual Meeting vote “FOR”annual meeting is required to approve the Amended and Restated Certificate of Incorporation. Shares that are voted “abstain” are treated as the same as voting “against” this proposal.
A proxy submitted by a stockholder may indicate that the shares represented by the proxy are not being voted (stockholder withholding) with respect to a particular matter. In addition, a broker may not be permitted to vote on shares held in street name on a particular matternon-routine matters in the absence of instructions from the beneficial owner of the stock (broker non-vote). At this meeting, only the ratification of the appointment of KPMG LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2023, is considered a routine matter. The other proposals presented at the Annual Meeting are non-routine matters, and therefore a broker may not vote on these matters absent instructions from the beneficial owner of the stock. The shares subject to a proxy which are not being voted on a particular matter because of either stockholder withholding or broker non-votes will count for purposes of determining the presence of a quorum, but are not treated as votes cast and, therefore, will have no effect on the election of directors, or the ratification of the appointment of KPMG LLP.LLP, but will have the effect of an "against" vote for the proposal to approve the Amended and Restated Certificate of Incorporation. Abstentions are voted neither “for” nor “against” a matter, and, therefore, will have no effect on the election of directors or the ratification of the appointment of KPMG LLP, but arewill have the effect of an “against” vote for the proposal to approve the Amended and Restated Certificate of Incorporation. Abstentions will also be counted in the determination of a quorum.
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Recommendations of the Board of Directors on Each of the Proposals Scheduled to be Voted on at the Annual Meeting
The Board of Directors recommends that you vote FOR the election of each of the Class IIII directors named in this proxy statement (Proposal 1) and, FOR the ratification of the appointment of KPMG LLP as our independent registered public accounting firm for the fiscal year ending December 31, 20212023 (Proposal 2), and FOR the approval of the amendment to our Certificate of Incorporation (Proposal 3).
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None of the directors or executive officers has any substantial interest in any matter to be acted upon, other than elections to office with respect to the directors nominated in Proposal 1.
Voting Instructions; Voting of Proxies
If you are a stockholder of record, you may:
| vote online at the Annual Meeting |
| vote through the internet or by telephone – in order to do so, please follow the instructions shown on your proxy card or Notice of Internet Availability; or |
| vote by mail – if you request or receive a paper proxy card and voting instructions by mail, simply complete, sign and date the proxy card and return it as soon as possible before the Annual Meeting in the envelope provided. |
Votes submitted through the internet or by telephone must be received by 11:59 p.m., Eastern Time, on May 26, 2021.24, 2023. Submitting your proxy, whether by telephone, through the internet or by mail if you requested or received a paper proxy card, will not affect your right to vote online should you decide to attend the virtual Annual Meeting. If you are not the stockholder of record, please refer to the voting instructions provided by your nominee to direct how to vote your shares. If your shares are held in an account with a brokerage firm, bank or other nominee, then you are deemed to be the beneficial owner of your shares and the broker that actually holds the shares for you is the record holder and is required to vote the shares it holds on your behalf according to your instructions. The proxy materials, as well as voting and revocation instructions, should have been forwarded to you by the bank, broker or other nominee that holds your shares. In order to vote your shares, you will need to follow the instructions that your bank, broker or other nominee provides you. The voting deadlines and availability of telephone and Internet voting for beneficial owners of shares held in street name will depend on the voting processes of the bank, broker or other nominee that holds your shares. Therefore, we urge you to carefully review and follow the voting instruction card and any other materials that you receive from that organization.
For Proposal 1, you may either vote “FOR” all of the nominees to the Board of Directors, or you may withhold your vote from any nominee you specify. For Proposal 2, you may vote “FOR” or “AGAINST” or “ABSTAIN” from voting. For Proposal 3, you may vote “FOR” or “AGAINST” or “ABSTAIN” from voting. Your vote is important. Whether or not you plan to attend the Annual Meeting, we urge you to vote by proxy to ensure that your vote is counted.
All proxies will be voted in accordance with the instructions specified on the proxy card. If you sign a physical proxy card and return it without instructions as to how your shares should be voted on a particular proposal at the Annual Meeting, your shares will be voted in accordance with the recommendations of our Board of Directors stated above.
If you do not vote and you hold your shares in street name, and your broker does not have discretionary power to vote your shares, your shares may constitute “broker non-votes” (as described above) and will not be counted in determining the number of shares necessary for approval of the proposals. However, shares that constitute broker non-votes will be counted for the purpose of establishing a quorum for the Annual Meeting.
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If you receive more than one proxy card or Notice of Internet Availability, your shares are registered in more than one name or are registered in different accounts. To make certain all of your shares are voted, please follow the instructions included on each proxy card or Notice of Internet Availability and vote each proxy card by telephone, through the internet or by mail. If you requested or received paper proxy materials by mail, please complete, sign, date and return each proxy card to ensure that all of your shares are voted.
Expenses of Soliciting Proxies
We will pay the expenses associated with soliciting proxies. Following the original distribution and mailing of the solicitation materials, we or our agents may solicit proxies by mail, email, telephone, facsimile, by other similar means, or in person. Our directors, officers and other employees, without additional compensation, may solicit proxies personally or in writing, by telephone, email or otherwise. Following the original distribution and mailing of the solicitation materials, we will request brokers, custodians, nominees and other record holders to forward copies of those materials to persons for whom they hold shares and to request authority for the exercise of proxies. In such cases, we, upon the request of the record holders, will reimburse such holders for their reasonable expenses. If you choose to access the proxy materials and/or vote through the internet, you are responsible for any internet access charges you may incur.
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Revocability of Proxies
A stockholder of record who has given a proxy may revoke it at any time before the closing of the polls by the inspector of elections at the Annual Meeting by:
| delivering to our Corporate Secretary (by any means, including facsimile) a written notice stating that the proxy is revoked; |
| signing and delivering a proxy bearing a later date; |
| voting again through the internet or by telephone; or |
| attending and voting online at the Annual Meeting by following the instructions posted at www.virtualshareholdermeeting.com/ |
Please note, however, that if your shares are held of record by a brokerage firm, bank or other nominee, and you wish to revoke a proxy, you must contact that firm to revoke or change any prior voting instructions.
Electronic Access to the Proxy Materials
The Notice of Internet Availability will provide you with instructions regarding how to:
| view our proxy materials for the meeting through the internet; |
| instruct us to mail paper copies of our current or future proxy materials to you; and |
| instruct us to send our current or future proxy materials to you electronically by email. |
Choosing to receive your future proxy materials by email will reduce the impact of our annual meetings of stockholders on the environment and lower the costs of printing and distributing our proxy materials. If you choose to receive future proxy materials by email, you will receive an email next year with instructions containing a link to those materials and a link to the proxy voting site. Your election to receive proxy materials by email will remain in effect until you terminate it.
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Voting Results
Voting results will be tabulated and certified by the inspector of elections appointed for the Annual Meeting. The final results will be tallied by the inspector of elections and filed with the SEC in a Current Report on Form 8-K within four business days of the Annual Meeting.
Implications of Being an “Emerging Growth Company” and “Smaller Reporting Company”
We are an “emerging growth company” as that term is used in the Jumpstart Our Business Startups Act of 2012, and a “smaller reporting company” as defined under Rule 405 of the Securities Act of 1933, and, as such, have elected to comply with certain reduced public company reporting requirements. These reduced reporting requirements include reduced disclosure about the company’s executive compensation arrangements and no requirement to have non-binding advisory votes on executive compensation.
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CORPORATE GOVERNANCE STANDARDS AND DIRECTOR INDEPENDENCE
We are committed to good corporate governance practices. These practices provide an important framework within which our Board of Directors and management pursue our strategic objectives for the benefit of our stockholders.
Corporate Governance Guidelines
Our Board of Directors has adopted Corporate Governance Guidelines that set forth expectations for directors, director independence standards, Board committee structure and functions, and other policies for the governance of the company. Our Corporate Governance Guidelines are available without charge on the investor relations section of our website at https://investors.passagebio.com/corporate-governance/documents-and-charters.
Board Composition and Leadership Structure
Our Corporate Governance Guidelines provide that our Board of Directors shall be free to choose its chairperson in any way that it considers in the best interests of our company, and that the Nominating and Governance Committee shall periodically consider the leadership structure of our Board of Directors and make such recommendations to the Board of Directors with respect thereto as the Nominating and Governance Committee deems appropriate. Our Corporate Governance Guidelines also provide that, when the positions of chairperson and Chief Executive Officer are held by the same person, the independent directors may designate a “lead independent director.” In cases in which the chairperson and Chief Executive Officer are the same person, the chairperson schedules and sets the agenda for meetings of the Board of Directors in consultation with the lead independent director, and the chairperson, or if the chairperson is not present, the lead independent director, chairs such meetings. In addition, the responsibilities of the lead independent director include: presiding over executive sessions of independent directors; serving as a liaison between the chairperson and the independent directors; being available, under appropriate circumstances, for consultation and direct communication with stockholders; and performing such other functions and responsibilities as requested by the Board of Directors from time to time.
The positions of Chief Executive Officer and Chair of our Board of Directors are held by two different individuals (Bruce Goldsmith,(William Chou, M.D. and Maxine Gowen, Ph.D. and Tadataka Yamada, M.D., respectively). This structure allows our Chief Executive Officer to focus on our day-to-day business while our Chair leads our Board of Directors in its fundamental role of providing advice to and independent oversight of management. Our Board of Directors believes such separation is appropriate, as it enhances the accountability of the Chief Executive Officer to the Board of Directors and strengthens the independence of the Board of Directors from management. Any changes to the leadership structure of our Board of Directors, if made, will be promptly disclosed on the Investor Relations section of our website and in our proxy materials. Our Board of Directors, in its sole discretion, may seek input from our stockholders on the leadership structure of our Board of Directors.
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Cybersecurity Risk Oversight
Securing the information of participants in our studies, medical professionals, employees, service providers, and other third parties is important to us. We have adopted physical, technological, and administrative controls on data security, and have a defined procedure for data incident detection, containment, response, and remediation. While everyone at our Company plays a part in managing these risks, oversight responsibility is shared by our Board of Directors, our Audit Committee, and management.
Board’s Role in Risk Oversight
Our Board of Directors believes that open communication between management and the Board of Directors is essential for effective risk management and oversight. Our Board of Directors meets with our Chief Executive Officer and other members of the senior management team at least quarterly at Board of Director meetings where among other topics, they discuss strategy and oversight on areas of material risk to the Company, including operational, research and development activities, financial, legal and regulatory, competitive, and strategic and reputational risks in the context of reports from the management team and evaluate the risks inherent in significant transactions. While our Board of Directors is ultimately responsible for risk oversight, our Board committees assist the Board of Directors in fulfilling its oversight responsibilities in certain areas of risk.
The Audit Committee assists our Board of Directors in fulfilling its oversight responsibilities with respect to risk management in the areas of internal control over financial reporting, disclosure controls and procedures and certain corporate, cybersecurity, legal and regulatory risks. On an annual basis, our Audit Committee reviews the management team’s assessment of business risk, compliance risks and disclosure control and procedure risks, with an emphasis on short-term and intermediate-term risks, and summarizes and discusses these risks with our Board of Directors. The Compensation Committee assists our Board of Directors in assessing risks created by the incentives inherent in our compensation policies. The Nominating and Governance Committee assists our Board of Directors in fulfilling its oversight responsibilities with respect to corporate governance and the management of certain corporate, legal and regulatory risks.risks, including environmental, social and corporate governance matters.
Director Independence
Our common stock is listed on the Nasdaq Global Select Market. Under the rules of the Nasdaq Stock Market, independent directors must constitute a majority of a listed company’s Board of Directors. In addition, the rules of the Nasdaq Stock Market require that, subject to specified exceptions, each member of a listed company’s Audit, Compensation and Nominating and Governance Committees must be an “independent director”. Under the rules of the Nasdaq Stock Market, a director will only qualify as an “independent director” if, in the opinion of that company’s Board of Directors, that person does not have a relationship that would interfere with the exercise of independent judgment in carrying out the responsibilities of a director. Additionally, Compensation Committee members must not have a relationship with the listed company that is material to the director’s ability to be independent from management in connection with the duties of a Compensation Committee member.
Audit Committee members must also satisfy the independence criteria set forth in Rule 10A-3 under the Securities Exchange Act of 1934, as amended (Exchange Act).
Our Board of Directors has undertaken a review of the independence of each director and considered whether each director has a material relationship with us that could compromise his or her ability to exercise independent judgment in carrying out his or her responsibilities. As a result of this review, our Board of Directors determined that Athena
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Countouriotis, Maxine Gowen, Patrick Heron, Saqib Islam, Michael Kamarck, Sandip Kapadia, Liam Ratcliffe,Derrell Porter and Tom Woiwode, and Tadataka Yamada, representing eightseven of our nineeight incumbent directors, are “independent directors” as defined under the applicable rules and regulations of the SEC and the listing requirements and rules of the Nasdaq Stock Market. Our Board of Directors has also determined that Derrell Porter, a nominee for our Board of Directors, is an “independent director” as defined under the applicable rules and regulations of the SEC and the listing requirements and rules of the Nasdaq Stock Market. In making these determinations, our Board of Directors reviewed and discussed information provided by the directors and us with regard to each directors’director’s business and personal activities and relationships as they may relate to us and our management, including the beneficial ownership of our capital stock by each non-employee director and any affiliates.
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Committees of Our Board of Directors
Our Board of Directors has established an Audit Committee, a Compensation Committee and a Nominating and Governance Committee, each of which has the composition and responsibilities described below. Members serve on these committees until their resignation or until otherwise determined by our Board of Directors. Each of these committees has a written charter, copies of which are available without charge on the investor relations section of our website at https://investors.passagebio.com/corporate-governance/documents-and-charters.
Audit Committee
Our Audit Committee is composed of Mr. Islam, Mr. Kapadia, and Dr. Porter. Mr. Kapadia is the Chair of our Audit Committee. The composition of our Audit Committee meets the requirements for independence under the current Nasdaq Stock Market and SEC rules and regulations. Each member of our Audit Committee is financially literate. In addition, our Board of Directors has determined that Mr. Kapadia is an “audit committee financial expert” as defined in Item 407(d)(5)(ii) of Regulation S-K promulgated under the Securities Act. Our Audit Committee is directly responsible for, among other things:
| selecting and hiring our independent registered public accounting firm; |
| the qualifications, independence and performance of our independent auditors; |
| the preparation of the audit committee report to be included in our annual proxy statement; |
| our compliance with certain legal and regulatory requirements, including disclosure controls; |
| assisting the Board of Directors with risk assessment and management, including cybersecurity risk management; |
| · | our accounting and financial reporting processes, including our financial statement audits and the integrity of our financial statements; and |
| reviewing and approving related-person transactions. |
Compensation Committee
Our Compensation Committee is composed of Dr. Woiwode,Countouriotis, Dr. CountouriotisGowen and Dr. Yamada.Woiwode. Dr. WoiwodeCountouriotis is the Chair of our Compensation Committee. The composition of our Compensation Committee meets the requirements for independence under the current Nasdaq Stock Market and SEC rules and regulations. Our Compensation Committee is responsible for, among other things:
| evaluating, recommending, approving and reviewing executive officer compensation arrangements, plans, policies and programs; |
| evaluating and |
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| overseeing our compliance with regulatory requirements associated with the compensation of directors, officers and employees. |
The Compensation Committee has the sole authority and responsibility, subject to any approval by the Board of Directors which the Compensation Committee or legal counsel determines to be desirable or required by applicable law or the Nasdaq rules, to determine all aspects of executive compensation packages for the Chief Executive Officer and other executive officers. The Compensation Committee also makes recommendations to our Board of Directors regarding the form and amount of compensation of non-employee directors. The Compensation Committee may take into account the recommendations of the Chief Executive Officer with respect to compensation of the other executive officers, and the recommendations of the Board of Directors or any member of the Board of Directors with respect to compensation of the Chief Executive Officer and other executive officers.
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The Compensation Committee engaged an independent executive compensation consulting firm, Radford, which is part of the RewardsAon’s Human Capital Solutions practice, ata division of Aon plc (formerly known as Radford) (Aon), effective until June 2022, to evaluate our executive compensation and Board of Directors compensation program and practices and to provide advice and ongoing assistance on these matters for the fiscal year ended December 31, 2020.assistance. Specifically, RadfordAon was engaged to:
| provide compensation-related data for a peer group of companies to serve as a basis for assessing competitive compensation practices; |
| review and assess our current Board of Directors, Chief Executive Officer and other executive officer compensation policies and practices and equity profile, relative to market practices; |
| review and assess our current executive compensation program relative to market to identify any potential changes or enhancements to be brought to the attention of the Compensation Committee; and |
| review market practices regarding base salary, bonus and equity programs. |
The Compensation Committee engaged an independent executive compensation consulting firm, Pearl Meyer and Partners, LLC., (“Pearl Meyer”), starting in June 2022, to evaluate our executive compensation and Board of Directors compensation program and practices and to provide advice and ongoing assistance on these matters. Specifically, Pearl Meyer was engaged to:
| · | review and assess the compensation provided to our Chief Executive Officer appointed during the fiscal year. |
Representatives of RadfordAon or Pearl Meyer met informally with the Chair of the Compensation Committee and attended the regular meetings of the Compensation Committee, including executive sessions from time to time without any members of management present. During the fiscal year ended December 31, 2020, Radford2022, Aon or Pearl Meyer worked directly with the Compensation Committee (and not on behalf of management) to assist the committee in satisfying its responsibilities and undertook no projects for management without the committee’s prior approval. The Compensation Committee has determined that none of the work performed by RadfordAon or Pearl Meyer during the fiscal year ended December 31, 20202022 raised any conflict of interest.
Nominating and Governance Committee
Our Nominating and Governance Committee is composed of Dr. Ratcliffe, Mr. HeronGowen, Dr. Kamarck and Dr. Yamada.Porter. Dr. RatcliffeGowen is the Chair of our Nominating and Governance Committee. Following our Annual Meeting, we expect to appoint Ms. Gowen to our Nominating and Governance Committee. Our Nominating and Governance Committee is responsible for, among other things:
| identifying, considering and recommending candidates for membership on our Board of Directors; |
| overseeing the process of evaluating the performance of our Board of Directors; and |
| advising our Board of Directors on corporate governance matters, including environmental, social and |
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Codes of Conduct and Ethics
Our Board of Directors has adopted a code of conduct and ethics that applies to all of our employees, officers and directors, including our Chief Executive Officer, Chief Financial Officer and other executive and senior financial officers. We intend to disclose future amendments to certain provisions of our code of conduct and ethics, or waivers of these provisions, on our website or in public filings to the extent required by the applicable rules. The full text of our code of conduct and ethics is posted on the investor relations section of our website at https://investors.passagebio.com/corporate-governance/documents-and-charters.
Anti-hedging
We have adopted an Insider Trading Policy that that applies to all of our employees, officers and directors, including our Chief Executive Officer and other executive officers, which prohibits such individuals from purchasing financial instruments, or otherwise engaging in transactions, that hedge or offset, or are designed to hedge or offset, any decrease in market value of our common stock, such as prepaid variable forward contracts, equity swaps, collars, forward sale contracts and exchange funds.
Compensation Committee Interlocks and Insider Participation
During 2020,2022, Dr. Countouriotis, Dr. Gowen and Dr. Woiwode Dr. Countouriotis and Dr. Yamada served on our Compensation Committee. None of our current executive officers has served as a member of the Board of Directors, or as a member of the Compensation or similar committee, of any entity that has one or more executive officers who served on our Board of Directors or Compensation Committee during the fiscal year ended December 31, 2020.2022.
Board and Committee Meetings and Attendance
The Board of Directors and its committees meet regularly throughout the year and also hold special meetings and act by written consent from time to time. During 2020,2022, the Board of Directors held eighteleven meetings including telephonic meetings; the Audit Committee held sixfive meetings; the Compensation Committee held fivesix meetings; and the Nominating and Governance Committee held three meeting.five meetings. During 2020, none of the directors2022, each director other than Saqib Islam attended fewer thanat least 75% of the aggregate of the total number of meetings held by the Board of Directors during his or her tenure and the total number of meetings held by all committees of the Board of Directors on which such director served during his or her tenure. The independent members of the Board of Directors also meet separately without management directors on a regular basis to discuss such matters as the independent directors consider appropriate.
Board Attendance at Annual Stockholders’ Meeting
We invite and encourage each member of our Board of Directors to attend our annual meetings of stockholders. We do not have a formal policy regarding attendance of our annual meetings of stockholders by the members of our Board of Directors. Six of the seven members of our Board of Directors attended our 2022 Annual Meeting of Stockholders.
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Communication with Directors
Stockholders and interested parties who wish to communicate with our Board of Directors, non-management members of our Board of Directors as a group, a committee of the Board of Directors or a specific member of our Board of Directors (including our Chair) may do so by letters addressed to:
Passage Bio, Inc.
c/o Corporate Secretary
One Commerce Square
2005 Market Street, 39th Floor
Philadelphia, PA 19103
All communications by letter addressed to the attention of our Corporate Secretary will be reviewed by the Corporate Secretary and provided to the members of the Board of Directors unless such communications are unsolicited items, sales materials and other routine items and items unrelated to the duties and responsibilities of the Board of Directors.
Considerations in Evaluating Director Nominees
The Nominating and Governance Committee is responsible for identifying, considering and recommending candidates to the Board of Directors for Board membership. A variety of methods are used to identify and evaluate director nominees, with the goal of maintaining and further developing a diverse, experienced and highly qualified Board of Directors. Candidates may come to our attention through current members of our Board of Directors, professional search firms, stockholders or other persons.
The Nominating and Governance Committee will recommend to the Board of Directors for selection all nominees to be proposed by the Board of Directors for election by the stockholders, including approval or recommendation of a slate of director nominees to be proposed by the Board of Directors for election at each annual meeting of stockholders, and will recommend all director nominees to be appointed by the Board of Directors to fill interim director vacancies.
Our Board of Directors encourages the selection of directors who will contribute to the company’s overall corporate goals. The Nominating and Governance Committee may from time to timetime-to-time review and recommend to the Board of Directors the desired qualifications, expertise and characteristics of directors, including such factors as business experience, diversity and personal skills in life sciences and biotechnology, finance, marketing, financial reporting and other areas that are expected to contribute to an effective Board of Directors. Exceptional candidates who do not meet all of these criteria may still be considered. In evaluating potential candidates for the Board of Directors, the Nominating and Governance Committee considers these factors in the light of the specific needs of the Board of Directors at that time.
In addition, under our Corporate Governance Guidelines, a director is expected to spend the time and effort necessary to properly discharge such director’s responsibilities. Accordingly, a director is expected to regularly attend meetings of the Board of Directors and committees on which such director sits, and to review prior to meetings material distributed in advance for such meetings. Thus, the number of other public company boards and other boards (or comparable governing bodies) on which a prospective nominee is a member, as well as his or her other professional responsibilities, will be considered. Also, under our Corporate Governance Guidelines, there are no limits on the number of three-year terms that may be served by a director. However, in connection with evaluating recommendations for nomination for reelection, the Nominating and Governance Committee considers director tenure. We value diversity on a company-wide basis but have not adopted a specific policy regarding Board diversity.
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Stockholder Recommendations for Nominations to the Board of Directors
The Nominating and Governance Committee will consider properly submitted stockholder recommendations for candidates for our Board of Directors who meet the minimum qualifications as described above. The Nominating and Governance Committee does not intend to alter the manner in which it evaluates candidates, including the minimum criteria set forth above, based on whether or not the candidate was recommended by a stockholder. A stockholder of record can nominate a candidate for election to the Board of Directors by complying with the procedures in Article I,
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Section 1.12 of our bylaws.Amended and Restated Bylaws (the Bylaws). Any eligible stockholder who wishes to submit a nomination should review the requirements in the bylawsBylaws on nominations by stockholders. Any nomination should be sent in writing to our Corporate Secretary, Passage Bio, Inc., One Commerce Square, 2005 Market Street, 39th Floor, Philadelphia, PA 19103. Submissions must include the full name of the proposed nominee, complete biographical information, a description of the proposed nominee’s qualifications as a director, other information regarding the nominee and proposing stockholder as specified in our bylaws,the Bylaws, and a representation thatcertain representations regarding the nominating stockholder is a beneficial or record holder of our stock.nomination. Any such submission must be accompanied by the written consent of the proposed nominee to be named as a nominee and to serve as a director if elected. These candidates are evaluated at meetings of the Nominating and Governance Committee and may be considered at any point during the year. If any materials are provided by a stockholder in connection with the recommendation of a director candidate, such materials are forwarded to the Nominating and Governance Committee.
Additional information regarding the process for properly submitting stockholder nominations for candidates for membership on our Board of Directors is set forth below under “Stockholder Proposals to Be Presented at Next Annual Meeting.” In addition to satisfying the foregoing requirements under the Bylaws, to comply with the universal proxy rules, stockholders who intend to solicit proxies in support of director nominees other than the Company’s nominees for the 2024 Annual Meeting of Stockholders must provide notice that sets forth the information required by Rule 14a-19 under the Exchange Act.
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ELECTION OF CLASS IIII DIRECTORS
Our Board of Directors is divided into three classes. Each class serves for three years, with the terms of office of the respective classes expiring in successive years. Directors and director nominees in Class IIII will stand for election at this Annual Meeting. The terms of office of directors in Class III and Class IIIII do not expire until the annual meetings of stockholders to be held in 20222024 and 2023,2025, respectively. Our Nominating and Governance Committee recommended to our Board of Directors, and our Board of Directors nominated Dr. GoldsmithCountouriotis, Mr. Islam, and Dr. Yamada,Mr. Kapadia, each an incumbent Class IIII director, and Dr, Porter for election as Class IIII directors at the Annual Meeting. At the recommendation of our Nominating and Governance Committee, our Board of Directors proposes that each of the Class IIII nominees be elected as a Class IIII director for a three-year term expiring at the annual meeting of stockholders to be held in 20242026 and until such director’s successor is duly elected and qualified or until such director’s earlier resignation or removal.
Each director will be elected by a plurality of the votes present online at the virtual Annual Meeting or represented by proxy at the Annual Meeting and entitled to vote on the election of directors. This means that the three individuals nominated for election to the Board of Directors at the Annual Meeting receiving the highest number of “FOR” votes will be elected. You may either vote “FOR” one, two or all of the nominees or “WITHHOLD” your vote with respect to one, two or all of the nominees. A “WITHHOLD” vote will have the same effect as an abstention. Shares represented by proxies will be voted “FOR” the election of each of the Class IIII nominees, unless the proxy is marked to withhold authority to so vote. You may not cumulate votes in the election of directors. If any nominee for any reason is unable to serve, the proxies may be voted for such substitute nominee as the proxy holders, who are officers of our company, might determine. Each nominee has consented to being named in this proxy statement and to serve if elected. Proxies may not be voted for more than three directors.
Nominees to the Board of Directors
The nominees and their ages as of December 31, 20202022 are provided in the table below. Additional biographical information for each nominee is set forth in the text below the table.
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Bruce A. Goldsmith, Ph.D., has served as our Chief Executive Officer and President and as a member of our board of directors since January 2020. Dr. Goldsmith served as an Advisor and Venture Partner at Deerfield Ventures from January 2019 to January 2020. From April 2019 to January 2020, Dr. Goldsmith also served as Interim Chief Executive Officer of Civetta Therapeutics. Prior to that, Dr. Goldsmith served initially as Chief Business Officer and then as Chief Operating Officer at Lycera, Corp. from April 2013 to January 2019. From 2008 to 2012, Dr. Goldsmith served as Vice President and then Senior Vice President of Corporate Development at Allos Therapeutics. Prior to Allos, Dr. Goldsmith served in various leadership roles at GPC Biotech in 2007 and Tibotec Therapeutics, a subsidiary of Johnson & Johnson, from 2005 to 2007. Dr. Goldsmith also previously held various positions at Johnson & Johnson in oncology global strategic marketing, business development and licensing and acquisition finance. Prior to joining Johnson & Johnson, Dr. Goldsmith was a research fellow at Novartis Pharma, K.K., where he conducted scientific research in a neurodegeneration drug discovery group. Dr. Goldsmith received a B.A. in Biology from Colgate University, a Ph.D. in Biology with a research thesis in neuroscience from the University of Pennsylvania, and an M.B.A. from Columbia University. We believe that Dr. Goldsmith is qualified to serve on our board of directors due to his experience in the biopharmaceutical and biotechnology industry.
Derrell D. Porter, M.D. currently serves as Founder & CEO at Cellevolve Bio, Inc., which was incorporated in March 2020. Prior to that, Dr. Porter served as SVP and Head of Commercial at Atara Biotherapeutics, Inc. from May 2017 to
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October 2019. Prior to joining Atara, Dr. Porter served as a Vice President with Gilead Sciences from April 2013 to May 2017, where he was responsible for corporate strategy, commercial planning, and global launch preparation for all of Gilead’s therapeutic areas. Previously, Dr. Porter was at AbbVie and Amgen, where he served in multiple US, EU and global roles of increasing responsibility in strategy, corporate development, business unit management, and sales & marketing. Dr. Porter began his career at McKinsey & Company in Los Angeles as part of the West Coast Health Care Practice. Dr. Porter currently serves on the boards of directors of several private companies. Dr. Porter holds an MD from the University of Pennsylvania, where he was a Twenty First Century Scholar, an MBA from The Wharton School and a bachelor’s degree in neuroscience from UCLA. We believe Dr. Porter is qualified to serve on our board of directors due to his biopharmaceutical, corporate development and global marketing experience.
Tadataka Yamada, M.D. has served as Chairman of our board of directors since July 2017. Dr. Yamada has served as a Venture Partner at Frazier Life Sciences since June 2015. From September 2017 to January 2020, Dr. Yamada served in a non-employee capacity as our President and Treasurer. From June 2011 to June 2015, Dr. Yamada served as the Chief Medical and Scientific Officer of Takeda Pharmaceutical Company Ltd. From 2006 to 2011, Dr. Yamada served as President of the Global Health Program of the Bill & Melinda Gates Foundation. Previously, Dr. Yamada served as Chairman of Research and Development of GlaxoSmithKline Inc., a multinational pharmaceutical company, and he previously held research and development positions at SmithKline Beecham. Prior to that, Dr. Yamada served as Chairman of the Department of Internal Medicine at the University of Michigan Medical School and Physician-in-Chief of the University of Michigan Medical Center. Dr. Yamada is a member of the National Academy of Medicine, a Fellow of the Imperial College of Medicine, a Master of the American College of Physicians, a Fellow of the Royal College of Physicians, a Member of the American Academy of Arts and Sciences and a past-President of the American Gastroenterological Association and the Association of American Physicians. Dr. Yamada currently serves on the boards of directors Athira Pharma, Inc. and Phathom Pharmaceuticals, Inc. Dr. Yamada previously served on the boards of directors of Takeda Pharmaceutical Company Ltd, GlaxoSmithKline PLC., CSL Limited, a biotechnology company, and Agilent Technologies, Inc., a scientific instrument manufacturing and clinical diagnostics company. Dr. Yamada received a B.A. in History from Stanford University and an M.D. from New York University School of Medicine. We believe that Dr. Yamada is qualified to serve on our board of directors due to his extensive research and experience in drug development, as well as his service as a director or officer of various biotechnology and biopharmaceutical companies.
Continuing Directors
The directors who are serving for terms that end following the Annual Meeting and their ages are provided in the table below. Additional biographical information for each nominee is set forth in the text below the table.
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Athena Countouriotis, M.D. M.D. has served as a member of our boardBoard of directorsDirectors since February 2020. Dr. Countouriotis has served as Chief Executive Officer of Avenzo Therapeutics since October 2022. Dr. Countouriotis served as Chief Executive Officer and a member of the boardBoard of directorsDirectors of Turning Point Therapeutics Inc. sincefrom September 2018 to August 2022, and from May 2018 to September 2018, she served as Chief Medical Officer of Turning Point Therapeutics. Dr. Countouriotis served as Senior Vice President and Chief Medical Officer for Adverum Biotechnologies, Inc. from June 2017 to May 2018, and before that served as Senior Vice President, Chief Medical Officer of Halozyme Therapeutics, Inc. from January 2015 to May 2017. Dr. Countouriotis also served as Chief Medical
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Officer of Ambit Biosciences Corporation from February 2012 until Ambit’s acquisition by Daiichi Sankyo Company in November 2014. Earlier in her career, Dr. Countouriotis led various clinical development organizations within Pfizer Inc. and Bristol-Myers Squibb Company for oncology therapeutics. Dr. Countouriotis currently serves on the boardBoard of directorsDirectors of Iovance Biotherapeutics, Inc., a public oncology therapeutics company, Recludix Therapeutics, Inc., a private oncology therapeutics company, Leal Therapeutics, Inc., a private central nervous system diseases company, and Capstan Therapeutics, Inc, a private cell therapy company. Dr. Countouriotis previously served on the boardBoard of directorsDirectors of Trovagene, Inc.,Cardiff Oncology, a public oncology therapeutics company.company, from 2017 – 2020. Dr. Countouriotis earned a B.S. from the University of California, Los Angeles, and an M.D. from Tufts University School of Medicine. Dr. Countouriotis received her initial training in pediatrics at the University of California, Los Angeles, and additional training at the Fred Hutchinson Cancer Research Center in the Pediatric Hematology/Oncology Program. We believe that Dr. Countouriotis is qualified to serve on our boardBoard of directorsDirectors due to her broad oncology biotech leadership experience and history of guiding multiple development programs to approval.
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Maxine Gowen, Ph.D. Saqib Islamhas served as a member of our boardBoard of directors since February 2021. Dr. Gowen has served as Chief Executive Officer of Tamuro Bio since July 2019. Dr. Gowen served as the founding President and Chief Executive Officer of Trevena, Inc. from 2007 to October 2018, and has served as a member of Trevena’s board of directors since 2008. Dr. Gowen previously held a variety of leadership roles at GlaxoSmithKline over a period of 15 years. She also currently serves on the boards of directors for Idera Pharmaceuticals, Inc., Akebia Therapeutics, Inc., and Aclaris Therapeutics, Inc., each a public biotechnology company, as well as two private companies. Dr. Gowen also currently serves on the board of directors of Life Sciences Pennsylvania, an industry association. Dr. Gowen received a B.Sc. in biochemistry from the University of Bristol, U.K., a Ph.D. in cell biology from the University of Sheffield, U.K., and an M.B.A. from the Wharton School of the University of Pennsylvania. We believe that Dr. Gowen is qualified to serve on our board of directors due to her leadership experiences in the life science and pharmaceutical industry.
Saqib Islam has served as a member of our board of directorsDirectors since March 2019. Mr. Islam has served as Chief Executive Officer and a member of the boardBoard of directorsDirectors of SpringWorks Therapeutics, Inc., a biopharmaceutical company, since August 2018, and from August 2017 to August 2018, he served as Chief Financial Officer and Chief Business Officer of SpringWorks. From February 2016 to August 2017, Mr. Islam served as Chief Business Officer at Moderna Therapeutics, Inc., a biotechnology company. From February 2013 to February 2016, Mr. Islam served as Executive Vice President, Chief Strategy and Portfolio Officer at Alexion Pharmaceuticals, Inc., a pharmaceutical company. Prior to joining Alexion, Mr. Islam worked for more than 25 years in international business management with a focus on business development, strategic decision-making and planning and capital markets, previously holding managing director positions at Morgan Stanley and Credit Suisse. Mr. Islam currently serves on the boardBoard of directorsDirectors of Silverback Therapeutics,ARS Pharmaceuticals, Inc., a publicly traded biotechnology company. Mr. Islam received a B.A. in Communications from McGill University and a J.D. from Columbia Law School. We believe that Mr. Islam is qualified to serve on our boardBoard of directorsDirectors due to his experience and expertise in operations management and executive leadership at various biopharmaceutical and biotechnology companies.
Sandip Kapadia has served as a member of our boardBoard of directorsDirectors since December 2019. Mr. Kapadia has served as the Chief Financial Officer of Harmony Biosciences Holdings, Inc. since March 2021. Mr. Kapadia previously served as the Chief Financial Officer for Intercept Pharmaceuticals, Inc. from July 2016 to March 2021. Previously, Mr. Kapadia served in various leadership capacities within finance over 19 years at Novartis International AG and Novartis affiliates in the United Kingdom, Netherlands, Switzerland and the U.S. Mr. Kapadia currently serves on the boardBoard of directorsDirectors of Molecular Partners AG and Vective Bio AG.AG, both public companies. Mr. Kapadia received a B.S. in Accounting from Montclair State University and an M.B.A. from Rutgers University, and is also a U.S. Certified Public Accountant. We believe that Mr. Kapadia is qualified to serve on our boardBoard of directorsDirectors due to his leadership experience in the biopharmaceutical industry and finance expertise.
Continuing Directors
The directors who are serving for terms that end following the Annual Meeting and their ages as of December 31, 2022 are provided in the table below. Additional biographical information for each nominee is set forth in the text below the table.
| Name | Age | Class | ||
| William Chou, M.D. | 50 | Class I Director | ||
| Maxine Gowen, Ph.D. (1)(2) | 65 | Class II Director | ||
| Michael Kamarck, Ph.D (3) | 71 | Class I Director | ||
| Derrell Porter, M.D. (3) (4) | 52 | Class I Director | ||
| Thomas Woiwode, Ph.D. (1) | 51 | Class II Director |
| (1) | Member of our Compensation Committee |
| (2) | Chairperson of our Nominating and Governance Committee |
| (3) | Member of our Nominating and Governance Committee |
| (4) | Member of our Audit Committee |
Liam Ratcliffe, M.D.William Chou, M.D. has served as our Chief Executive Officer and member of our Board of Directors since October 2022. Dr. Chou is an accomplished executive with nearly 20 years of healthcare experience across a range of development and commercialization roles. Dr. Chou previously served as CEO of Aruvant Sciences (Aruvant), a clinical-stage biopharmaceutical company focused on developing gene therapies for rare disease, from November 2019 to October 2022. Prior to joining Aruvant, from May 2008 to October 2019, Dr. Chou served in a variety of leadership roles at Novartis Pharma AG (Novartis), including Vice President and Global Disease Lead for Novartis’ Cell and Gene Therapy where he oversaw the global commercial launch of Kymriah®, the first CAR-T cell therapy. Prior to that role, Dr. Chou led the Kymriah® lymphoma clinical development program to approvals in the United States, Europe, Australia, Canada and Japan. Before joining Novartis, Dr. Chou worked at the Boston Consulting Group where he focused on commercial and clinical pharmaceutical strategy. Dr. Chou holds an MBA from the Yale School of Management, an MD from the University of Pittsburgh School of Medicine, and an AB in politics and economics from Princeton University. Dr. Chou completed his residency in internal medicine at Yale New Haven Hospital and his fellowship in geriatrics at Yale University.
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Maxine Gowen, Ph.D. has served as a member of our boardBoard of directorsDirectors since February 2021, and as Chairwoman of the Board since September 2019.2021. Dr. Ratcliffe hasGowen served as Chief Executive Officer of Tamuro Bio from July 2019 to December 2021. Dr. Gowen served as the Headfounding President and Chief Executive Officer of Biotechnology at Access Industries since April 2019. From SeptemberTrevena, Inc. from 2007 to October 2018, and served as a member of Trevena’s Board of Directors from 2008 to April 2019,2021. Dr. Ratcliffe served as Managing DirectorGowen previously held a variety of leadership roles at New Leaf Venture Partners,GlaxoSmithKline over a healthcare venture capital firm, where he focused on investing in therapeutics and therapeutic platform companies. Prior to joining New Leaf, Dr. Ratcliffe held various positionsperiod of increasing responsibility at Pfizer Inc., a multinational pharmaceutical corporation, including Senior Vice President and Development Head for Neuroscience, and Worldwide Head of Clinical Research and Development. Dr. Ratcliffe15 years. She also currently serves on the boardboards of directors of Arvinas,for Aceragen Inc., Merus N.V., and Aclaris Therapeutics, Inc., each a public biotechnology company, as well as one private company. Dr. RatcliffeGowen previously served on the boardsBoard of
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directorsBIO, an industry association, from 2008 – 2022, the Board of UnumDirectors of Akebia Therapeutics, Inc.Inc from 2014 – 2021, the Board of Directors and executive committee of Trevena, Inc from 2008 – 2021, and the Board of Directors and executive committee of Life Sciences Pennsylvania, an industry association from 2016 - 2021. Dr. Gowen received a B.Sc. in biochemistry from the University of Bristol, U.K., Edge Therapeutics, Inc.a Ph.D. in cell biology from the University of Sheffield, U.K., Array Biopharmaceuticals, Inc., Deciphera Pharmaceuticals, Inc. and Aptinyx Inc. Dr. Ratcliffe received an M.B.A. from the UniversityWharton School of Michigan and an M.D. and Ph.D. in Immunology from the University of Cape Town, and he completed his internal medicine training and fellowship in Immunology at Groote Schuur Hospital and associated teaching hospitals in Cape Town, South Africa.Pennsylvania. We believe that Dr. RatcliffeGowen is qualified to serve on our boardBoard of directorsDirectors due to his extensive experienceher leadership experiences in the venture capital industry, medicallife science and scientific background and training, and leadership at various biopharmaceutical and biotechnology companies.pharmaceutical industry.
Thomas Woiwode,Michael Kamarck, Ph.D., has served as a member of our boardBoard of Directors since July 2022. Dr. Kamarck is the Chairman of the Sanofi Biotech Advisory Council, providing strategic guidance to advance Sanofi’s biologicals business. He recently retired as Chief Technology Officer for Vir Biotechnology, Inc., where he led a multi-modality technical approach to the development of treatments of serious infectious diseases such as COVID-19 (sotrovimab), influenza and hepatitis B, from June 2017 to July 2021. Prior to joining Vir, Dr. Kamarck was the Senior Vice President of Global Vaccines and Biologics Manufacturing and President of Merck BioVentures from December 2009 to March 2012. In this role, he was responsible for the worldwide manufacturing network in support of the vaccine portfolio and biologics businesses. Dr. Kamarck also held numerous senior executive positions at Wyeth Pharmaceuticals, including President, Technical Operations and Product Supply as a member of the Wyeth Management Team. While with Wyeth, he was responsible for establishing a global biotechnology network of more than 10,000 employees to develop and manufacture numerous blockbuster products, including building the manufacturing infrastructure to deliver the global supply of Prevnar 13® and Enbrel®. Dr. Kamarck also spent 16 years at Bayer AG serving in numerous roles, including Senior Vice President of Operations for Bayer Biologicals. He has authored more than 50 peer-reviewed publications and has 20 issued patents. He currently serves on the Board of Directors of Vaxcyte, Inc., a public company and previously served on the Board of Directors of Trillium Therapeutics, Inc from 2020 – 2021. Dr. Kamarck holds a Ph.D. in biochemistry from the Massachusetts Institute of Technology and a bachelor’s degree in biology from Oberlin College. We believe that Dr. Kamarck is qualified to serve on our Board of Directors due to his extensive expertise and leadership in biopharmaceutical product development and manufacturing.
Derrell D. Porter, M.D. has served as a member of our Board of Directors since May 2021. Dr. Porter has served as Founder & CEO at Cellevolve Bio, Inc., a privately held biotechnology company, since December 2020. Prior to that, Dr. Porter served as SVP and Head of Commercial at Atara Biotherapeutics, Inc. from May 2017 to October 2019. Prior to joining Atara, Dr. Porter served as a Vice President with Gilead Sciences from April 2013 to May 2017, where he was responsible for corporate strategy, commercial planning, and global launch preparation for all of Gilead’s therapeutic areas. Previously, Dr. Porter was at AbbVie and Amgen, where he served in multiple US, EU and global roles of increasing responsibility in strategy, corporate development, business unit management, and sales & marketing. Dr. Porter began his career at McKinsey & Company in Los Angeles as part of the West Coast Health Care Practice. Dr. Porter currently serves on the boards of directors of several private companies. He currently serves on the Board of Directors of Acumen Pharmaceuticals, Inc., a public company and several private companies. Dr. Porter holds an M.D. from the University of Pennsylvania, where he was a Twenty First Century Scholar, an M.B.A. from The Wharton School and a Bachelor’s degree in neuroscience from UCLA. We believe Dr. Porter is qualified to serve on our Board of Directors due to his biopharmaceutical, corporate development and global marketing experience.
Thomas Woiwode, Ph.D. has served as a member of our Board of Directors since September 2018. Since 2002, Dr. Woiwode has served in various investment and operational roles at Versant Venture Management, LLC, a healthcare investment firm, since 2002, including serving as a Managing Director since July 2014 and a Venture Partner from 2011 to 2014. From 2011 to 2013, Dr. WoiwodeHe also served as the Chief Operating Officer of OkariosOkairos AG, a biopharmaceutical company. Previously,company developing genetic vaccines for major infectious diseases, from April 2011 until May 2013 when it was acquired by GlaxoSmithKline plc. Prior to Okairos, Dr. Woiwode co-founded EuroVentures, a wholly owned biotechnology incubator within Versant Venture Management, LLC,Ventures, and in this role, served as the founding Chief Business Officer for three biotechnology portfolio companies. Prior tocompanies created within Versant Ventures. Before joining Versant Ventures, Dr. Woiwode served as a Research Scientist at XenoPort, Inc., a biotechnologybiopharmaceutical company. Dr. WoiwodeHe currently serves on the boardsBoards of directorsDirectors of Gritstone Oncology,Aligos Therapeutics, Inc., Adverum Biotechnologies, Inc.Vectiv Bio Holdings AG and AligosTempest Therapeutics, Inc., as well as several private companies. Dr. WoiwodeHe previously served on the boardBoard of directorsDirectors of Audentes Therapeutics, Inc., Adverum Biotechnologies, Inc., Gritstone Oncology, Inc. and CrisprCRISPR Therapeutics AG, both publiceach publicly traded biotechnology companies. Dr. Woiwode receivedholds a B.A. in English and a B.S. in Chemistry from the University of California, Berkeley and a Ph.D. in Organic Chemistry as an NSF Fellow from Stanford University. We believe that Dr. Woiwode is qualified to serve on our boardBoard of directorsDirectors due to his educational background, experience as a board member and senior executive of biotechnology and pharmaceutical companies, and experience as an investor in new life sciences companies.
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Family Relationships
There are no familial relationships among any of our directors and executive officers.
Board Diversity Matrix
Our Board of Directors and each of the standing committees of our Board of Directors has diverse representation. In addition, on our Board of Directors there are three directors who hold medical doctorates, three directors who hold doctorates in scientific fields and four directors who hold a master’s in business administration. The table below provides certain highlights of the composition of our Board of Directors as of the date of this Proxy Statement, as reported by our directors. Each of the categories listed in the table below has the meaning set forth in Nasdaq Rule 5605(f).
| Board Diversity Matrix (As of April 3, 2023) | ||||||||||
| Total Number of Directors | 8 | |||||||||
| Female | Male | Did Not Disclose Gender | ||||||||
| Part I: Gender Identity | ||||||||||
| Directors | 1 | 6 | 1 | |||||||
| Part II: Demographic Background | ||||||||||
| African American or Black | 1 | |||||||||
| Asian | 3 | |||||||||
| White | 1 | 2 | ||||||||
| Did Not Disclose Demographic Background | 1 | |||||||||
Non-Employee Director Compensation
For the year ended December 31, 2020, our
Our non-employee directors receivedreceive the following compensation pursuant to a program adopted by our Board of Directors, which was paid quarterly in arrears and was pro-rated for partial quarters served:Directors:
| Cash Compensation. The program currently provides an annual cash retainer of |
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| Equity Compensation. Each new, non-employee director who joins our Board of Directors will receive an initial option grant for the purchase of |
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The following table sets forth the compensation earned by or paid to our non-employee directors for services provided during the year ended December 31, 2020.2022. Neither Dr. Goldsmith, our former President and Chief Executive Officer, nor Dr. Chou, our President and Chief Executive Officer, received no compensation for histheir service as a directordirectors during 2020.2022.
| Fees Earned or | ||||||||||||
| Paid in | Option | |||||||||||
| Name | Cash ($) | Awards(3) ($) | Total ($) | |||||||||
| Athena Countouriotis, M.D. | 48,750 | 31,094 | 79,844 | |||||||||
| Maxine Gowen, Ph.D. (1) | 182,886 | 83,752 | 266,638 | |||||||||
| Saqib Islam | 47,500 | 31,094 | 78,594 | |||||||||
| Michael Kamarck, Ph.D. | 22,000 | 89,466 | 111,466 | |||||||||
| Sandip Kapadia | 55,000 | 31,094 | 86,094 | |||||||||
| Derrell Porter, M.D. | 51,500 | 31,094 | 82,594 | |||||||||
| Tom Woiwode, Ph.D. | 48,029 | 31,094 | 79,123 | |||||||||
| Liam Ratcliffe, M.D., Ph.D. (2) | 8,764 | - | 8,764 | |||||||||
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| | Fees Earned or | | | | | | | |
| | Paid in | | Option | | | | ||
Name |
| Cash($) |
| Awards($)(1) |
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Carl L. Gordon, Ph.D., CFA (2) | | $ | — | | $ | — | | $ | — |
Patrick Heron (3) |
| | 46,500 |
| | 458,816 |
| | 505,316 |
Saqib Islam |
| | 42,500 |
| | 229,408 |
| | 271,908 |
Sandip Kapadia |
| | 50,000 |
| | 762,259 |
| | 812,259 |
Liam Ratcliffe, M.D., Ph.D. |
| | 43,000 |
| | 458,816 |
| | 501,816 |
Tom Woiwode, Ph.D. |
| | 45,000 |
| | 458,816 |
| | 503,816 |
Tadataka Yamada, M.D. |
| | 74,000 |
| | 458,816 |
| | 532,816 |
Athena Contouriotis, M.D. |
| | 33,205 |
| | 458,816 |
| | 492,021 |
| (1) | Dr. Gowen received $106,667 in cash compensation and an option award for the purchase of 40,000 shares of our common stock for service as the Company’s Interim Executive Chairwoman. |
| (2) | Dr. Ratcliffe resigned from our Board on March 7, 2022. |
| (3) | The amounts reported in this column represent the aggregate grant date fair value of the stock options granted to our non-employee directors during the year ended December 31, |
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| 74,754 | |
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| 102,378 | ||
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| 140,057 | ||
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| 48,000 | ||
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| 121,828 | ||
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| 57,836 | ||
Tom Woiwode, Ph.D. | 74,754 | |||
| Liam Ratcliffe, M.D., Ph.D.(6) | 0 | |||
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| (5) | For the year ended December 31, 2022. Dr. Kamarck received an option award for the purchase of 48,000 shares of common stock upon appointment to our Board of Directors, which is included within the table above. |
| (6) | Dr. |
OUR BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” THE ELECTION OF EACH OF THE NOMINATED CLASS IIII DIRECTORS.
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RATIFICATION OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
Our Audit Committee has selected KPMG LLP as our principal independent registered public accounting firm to perform the audit of our financial statements for the fiscal year ending December 31, 2021.2023. KPMG LLP audited our financial statements for the fiscal years ended December 31, 20202022 and 2019.2021. We expect that representatives of KPMG LLP will be present at the Annual Meeting, will be able to make a statement if they so desire and will be available to respond to appropriate questions.
At the Annual Meeting, the stockholders are being asked to ratify the appointment of KPMG LLP as our independent registered public accounting firm for the fiscal year ending December 31, 2021.2023. Although ratification by stockholders is not required by law, our Audit Committee is submitting the selection of KPMG LLP to our stockholders because we value our stockholders’ views on our independent registered public accounting firm and as a matter of good corporate governance. If this proposal does not receive the affirmative approval of a majority of the votes cast on the proposal, the Audit Committee would reconsider the appointment. Notwithstanding its selection and even if our stockholders ratify the selection, our Audit Committee, in its discretion, may appoint another independent registered public accounting firm at any time during the year if the Audit Committee believes that such a change would be in our best interests and the interests of our stockholders.
The following table presents fees for professional audit services rendered by KPMG LLP for the audit of our annual financial statements for the years ended December 31, 20202022 and 2019.2021.
Principal Accountant Fees and Services
| Fees Billed | Fiscal Year 2022 | Fiscal Year 2021 | ||||||
| Audit fees (1) | $ | 490,000 | $ | 535,000 | ||||
| Audit-related fees (2) | — | — | ||||||
| Tax fees (3) | — | — | ||||||
| All other fees (4) | — | — | ||||||
| Total fees | $ | 490,000 | $ | 535,000 | ||||
| | | | | | |
Fees Billed |
| Fiscal Year 2020 |
| Fiscal Year 2019 | ||
Audit fees(1) | | $ | 1,250,000 | | $ | 240,000 |
Audit-related fees(2) | |
| — | |
| — |
Tax fees(3) | |
| — | |
| — |
All other fees(4) | |
| — | |
| — |
Total fees | | $ | 1,250,000 | | $ | 240,000 |
| (1) | “Audit fees” include fees for professional services provided by KPMG LLP in connection with the audit of our financial statements, review of our quarterly financial statements, and related services that are typically provided in connection with registration |
| (2) | There were no “Audit-related fees” for fiscal years |
| (3) | There were no “Tax fees” for fiscal years |
| (4) | There were no other fees incurred |
| 17 |
Policy on Audit Committee Pre-Approval of Audit and Permissible Non-Audit Services of Independent Registered Public Accounting Firm
Our Audit Committee generally pre-approves all audit and permissible non-audit services provided by the independent registered public accounting firm. These services may include audit services, audit-related services, tax services and other services. Pre-approval is detailed as to the particular service or category of services and is generally subject to a specific budget. The independent registered public accounting firm and management are required to periodically report to the Audit Committee regarding the extent of services provided by the independent registered public accounting firm in accordance with this pre-approval, and the fees for the services performed to date. Our Audit Committee may also pre-approve particular services on a case-by-case basis. All of the services relating to the fees described in the table above were approved by our Audit Committee.
OUR BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” APPROVAL OF PROPOSAL NO. 2.
APPROVAL OF AMENDMENT TO CERTIFICATE OF INCORPORATION
Section 102(b)(7) of the General Corporation Law of the State of Delaware was amended effective August 1, 2022 to authorize exculpation of officers of Delaware corporations. Specifically, the amendment permits Delaware corporations to exculpate their officers, in addition to their directors, for personal liability for breach of the duty of care in certain actions. This exculpation would not protect officers from liability for breach of the duty of loyalty, acts or omissions not in good faith or that involve intentional misconduct or a knowing violation of law, or any transaction in which the officer derived an improper personal benefit. Nor would this exculpation shield such officers from liability for claims brought by or in the right of the corporation, such as derivative claims.
Our Board of Directors believes it is necessary to provide protection to officers to the fullest extent permitted by law in order to attract and retain highly-qualified senior leadership. The nature of the role of directors and officers often requires them to make decisions on crucial matters often in time-sensitive situations, which can create substantial risk of investigations, claims, actions, suits or proceedings seeking to impose liability on the basis of hindsight, especially in the current litigious environment and regardless of merit. Limiting concern about personal risk would empower both directors and officers to best exercise their business judgment in furtherance of stockholder interests. We expect competitor companies will likely adopt exculpation clauses that limit the personal liability of officers in their charters and failing to adopt the amendment could negatively affect our ability to recruit and retain high-caliber officer candidates.
The proposed amendment is not being proposed in response to any specific resignation, threat of resignation or refusal to serve by any director or officer. This protection has long been afforded to directors, and our Board of Directors believes that extending similar exculpation to its officers is fair and in the best interests of the Company and its stockholders. Accordingly, our Board of Directors has unanimously approved the Amended and Restated Certificate of Incorporation in the form attached hereto as Appendix A, and recommends that our stockholders vote “FOR” the proposed amendment.
OUR BOARD OF DIRECTORS RECOMMENDS A VOTE “FOR” APPROVAL OF PROPOSAL NO. 3.
| 18 |
16
The information contained in the following report of the Audit Committee is not considered to be “soliciting material,” “filed” or incorporated by reference in any past or future filing by us under the Securities Exchange Act of 1934, as amended, or the Securities Act of 1933, as amended, unless and only to the extent that we specifically incorporate it by reference.
The Audit Committee has reviewed and discussed with our management and KPMG LLP our audited financial statements as of and for the year ended December 31, 2020.2022. The Audit Committee has also discussed with KPMG LLP the matters required to be discussed by the applicable requirements of the Public Company Accounting Oversight Board (United States) and the U.S. Securities and Exchange Commission.
The Audit Committee has received and reviewed the written disclosures and the letter from KPMG LLP required by applicable requirements of the Public Company Accounting Oversight Board regarding the independent accountant’s communications with the Audit Committee concerning independence, and has discussed with KPMG LLP its independence.
Based on the review and discussions referred to above, the Audit Committee recommended to our Board of Directors that the audited financial statements as of and for the year ended December 31, 20202022 be included in our Annual Report on Form 10-K for the year ended December 31, 20202022 for filing with the U.S. Securities and Exchange Commission.
Submitted by the Audit Committee
Sandip Kapadia, Chair
Saqib Islam
Patrick HeronSandip Kapadia, Chair
Derrell Porter
| 19 |
17
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT
The following table sets forth certain information with respect to the beneficial ownership of our common stock as of March 31, 2021,15, 2023, by:
| each stockholder known by us to be the beneficial owner of more than 5% of our common stock; |
| each of our directors or director nominees; |
| each of our named executive officers; and |
| all of our directors and executive officers as a group. |
Percentage ownership of our common stock is based on 53,977,48454,617,523 shares of our common stock outstanding on March 31, 2021.15, 2023. We have determined beneficial ownership in accordance with the rules of the SEC, and thus it represents sole or shared voting or investment power with respect to our securities, and the information is not necessarily indicative of beneficial ownership for any other purpose. Unless otherwise indicated below, to our knowledge, the persons and entities named in the table have sole voting and sole investment power with respect to all shares that they beneficially owned, subject to community property laws where applicable. We have deemed all shares of common stock subject to options or other convertible securities held by that person or entity that are currently exercisable or that will become exercisable within 60 days of March 31, 202115, 2023 to be outstanding and to be beneficially owned by the person or entity holding the option for the purpose of computing the percentage ownership of that person or entity but have not treated them as outstanding for the purpose of computing the percentage ownership of any other person or entity. Unless otherwise indicated, the address of each beneficial owner listed in the table below is c/o Passage Bio, Inc., One Commerce Square, 2005 Market Street, 39th Floor, Philadelphia, PA 19103.
| Beneficial Ownership | ||||||||
| Name of Beneficial Owner | Number | Percent | ||||||
| 5% Stockholders | ||||||||
| Frazier Life Sciences IX, L.P. (1) | 3,756,915 | 6.9 | % | |||||
| Lynx1 Capital Management LP (2) | 3,355,917 | 6.1 | % | |||||
| OrbiMed and affiliated entities (3) | 8,931,999 | 16.4 | % | |||||
| Versant Ventures and affiliated entities (4) | 4,959,769 | 9.1 | % | |||||
| Directors and Named Executive Officers: | ||||||||
| William Chou, M.D. (5) | 12,679 | * | % | |||||
| Athena Countouriotis (6) | 69,654 | * | % | |||||
| Maxine Gowen, Ph.D. (7) | 64,706 | * | % | |||||
| Saqib Islam (8) | 121,057 | * | % | |||||
| Michael Kamarck, Ph.D (9) | 13,333 | * | % | |||||
| Sandip Kapadia (10) | 88,497 | * | % | |||||
| Derrell Porter, M.D. (11) | 21,617 | * | % | |||||
| Tom Woiwode, Ph.D. (12) | 5,010,523 | 9.2 | % | |||||
| Edgar B. (Chip) Cale (13) | 617,996 | 1.1 | % | |||||
| Alex Fotopoulos (14) | 617,594 | 1.1 | % | |||||
| Simona King (15) | 257,436 | * | % | |||||
| Bruce Goldsmith, Ph.D. (16) | 2,514,997 | 4.4 | % | |||||
| Monika (Maria) Toernsen (17) | 116,789 | * | % | |||||
| All executive officers and directors as a group (12 persons) (18) | 7,042,061 | 12.4 | % | |||||
| | | | | |
| | Beneficial Ownership |
| ||
Name of Beneficial Owner |
| Number |
| Percent |
|
5% Stockholders |
|
|
|
| |
FMR LLC (1) |
| 5,278,100 |
| 9.8 | % |
Frazier Life Sciences IX, L.P. (2) |
| 5,009,219 |
| 9.3 | % |
LAV Prescience Limited (3) |
| 2,827,328 |
| 5.2 | % |
OrbiMed and affiliated entities (4) |
| 6,262,899 |
| 11.6 | % |
Versant Ventures and affiliated entities (5) |
| 4,959,769 |
| 9.2 | % |
Directors and Named Executive Officers: |
|
|
|
| |
Bruce Goldsmith, Ph.D. (6) |
| 1,922,270 |
| 3.4 | % |
Stephen Squinto, Ph.D. (7) |
| 1,113,492 |
| 2.0 | % |
Jill M. Quigley (8) |
| 495,514 |
| * | % |
Gary Romano M.D., Ph.D. (9) |
| 378,893 |
| * | % |
Athena Countouriotis (10) |
| 32,998 |
| * | % |
Maxine Gowen, Ph.D. (11) |
| 2,820 |
| * | % |
Patrick Heron (12) |
| 5,023,317 |
| 9.3 | % |
Saqib Islam (13) |
| 66,454 |
| * | % |
Sandip Kapadia (14) |
| 44,587 |
| * | % |
Derrell Porter, M.D. |
| — |
| * | % |
Liam Ratcliffe, M.D., Ph.D. (15) |
| 16,898 |
| * | % |
Tom Woiwode, Ph.D. (16) |
| 4,973,867 |
| 9.2 | % |
Tadataka Yamada, M.D. (17) |
| 670,247 |
| 1.2 | % |
All executive officers and directors as a group (15 persons) (18) |
| 14,722,950 |
| 25.5 | % |
| 20 |
| * | Represents beneficial ownership of less than one percent. |
| (1) |
18
| Based solely on a Schedule 13D/A filed on |
| (2) | Based solely on a Schedule 13G/A filed on February 14, 2023. Represents (a) 3,355,917 shares of common stock held by Lynx1 Capital Management LP. The address for Lynx1 Capital Management LP is 151 Calle de San Francisco, Suite 200, PMB 1237, San Juan, PR 00901-1607. |
| (3) | Based solely on a Schedule |
| Based solely on a Schedule 13D filed on March 13, 2020. Represents (i) 4,026,417 shares of common stock beneficially owned by Versant Venture Capital VI, L.P. (“VVC VI”), and (ii) 933,352 shares of common stock beneficially owned by Versant Vantage I, L.P. (“VV I”). Versant Ventures VI GP, L.P. (“VV VI GP”) is the general partner of VVC VI, and Versant Ventures VI GP-GP, LLC (“VV VI GP-GP”) is the general partner of VV VI GP. Each of Bradley J. Bolzon, Jerel C. Davis, Kirk G. Nielsen, Clare Ozawa, Robin L. Praeger and Tom Woiwode Ph.D., as managing members of VV VI GP-GP, may be deemed to share voting and dispositive power over the shares held by VVC VI. Versant Vantage I GP, L.P. (“VV I GP”) is the general partner of VV I, and Versant Vantage I GP-GP, LLC (“VV I GP-GP”) is the general partner of VV I GP. Each of Bradley J. Bolzon, Jerel C. Davis, Clare Ozawa, Robin L. Praeger and Dr. Woiwode, as managing members of VV I GP- GP, may be deemed to share voting and dispositive power over the shares held by VV I. Dr. Woiwode is a Managing Director at Versant Ventures and a member of our |
| Represents |
19
| Represents (i) |
| Represents |
| Represents |
| Represents |
| Represents |
| Represents |
| Represents (i) |
| Represents (i) |
| Represents (i) |
| (15) | Represents (i) 251,186 shares underlying options to purchase common stock that are exercisable within 60 days of March 15, 2023, and (ii) 6,250 restricted stock units vesting within 60 days of March 15, 2023. |
| (16) | Represents (i) 15,965 shares of common stock and (ii) 2,499,032 shares underlying options to purchase common stock that are exercisable within 60 days of March 15, 2023. |
| (17) | Represents (i) 8,082 shares of common stock and (ii) 108,707 shares underlying options to purchase common stock that are exercisable within 60 days of March 15, 2023. |
| (18) | Represents (i) 5,018,337 shares of common stock and, (ii) 2,017,474 shares underlying options to purchase common stock that are exercisable within 60 days of March 15, 2023, and, (iii) 6,250 restricted stock units vesting within 60 days of March 15, 2023. |
| 21 |
20
The following table provides information regarding our executive officers as of March 31, 2021:2023:
|
|
|
|
|
| |||
| 50 |
|
| |||||
|
|
|
| President, Chief Executive Officer |
| |||
|
|
|
|
|
| |||
|
|
|
|
|
| |||
|
|
|
|
|
| |||
|
|
|
|
|
| |||
|
|
|
|
|
| |||
Edgar B. (Chip) Cale |
|
|
| General Counsel and Corporate Secretary | ||||
| Mark Forman, Ph.D. |
| 59 | Chief Medical Officer | |||||
| Alex Fotopoulos | 54 | Chief Technical Officer | ||||||
| Simona King | 51 | Chief Financial Officer |
Bruce A. Goldsmith, Ph.D.William Chou, M.D. has served as our President and Chief Executive Officer and President and as a member of our boardBoard of directorsDirectors since January 2020.October 2022. Dr. Goldsmith’sChou’s biographical information is set forth above under the heading “Proposal No. 1 – Election of Class IIII Directors – Nominees to the Board of Directors.”Continuing Directors”.
Jill M. Quigley Edgar B. (Chip) Cale has served as our Chief Operating OfficerGeneral Counsel since November 2018.September 2019 and Corporate Secretary since December 2019. From January 2017June to November 2018, Ms. QuigleyOctober 2022, Mr. Cale also served as our interim Chief Executive Officer of Nutrinia Ltd.,Officer. From June 1998 to July 2019, Mr. Cale served in various senior leadership roles at GlaxoSmithKline plc, a multinational pharmaceutical company, focused on the treatment of rare conditions of the gastrointestinal tract. From July 2012most recently as Senior Vice President, Legal Corporate Functions. Prior to December 2016, Ms. Quigleythis, Mr. Cale also served as SeniorVice President, and head of legal support for GSK’s worldwide business development, and Vice President, General Counsel of NPS Pharmaceuticals, a biotechnology company focused on developing treatments for rare diseases, which was acquired by Shire plc in March 2015. From 2011GSK Vaccines. Prior to 2012, Ms. Quigleythat, Mr. Cale served as Corporate Counsel for Pharmasset, Inc., a pharmaceutical company. Ms. Quigley currently serves oncorporate and securities lawyer supporting emerging growth companies in the board of directors of Terns Pharmaceuticals, Inc., a biopharmaceutical company. Ms. Quigley began her career as an associate with the law firm of Dechertlife science and technology industries at Venture Law Group LLP and later served as Assistant Corporate Counsel for Integra LifeSciences Holdings Corporation. Ms. QuigleyBrobeck, Phleger & Harrison LLP. Mr. Cale received a B.A. in Communications, Legal Institutions, Economics & Government (CLEG)Biology from Americanthe University of Pennsylvania and a J.D. from Rutgers School of Law.
Richard S. Morris has served as our Chief Financial Officer since October 2019. From November 2017 to July 2019, Mr. Morris served as Executive Vice President and Chief Financial Officer of Context Therapeutics, LLC, a biopharmaceutical company. From May 2014 to December 2016, Mr. Morris served as Chief Financial Officer of Vitae Pharmaceuticals, Inc., a biopharmaceutical company. Prior to that, Mr. Morris served in various leadership roles at ViroPharma Incorporated, including as Vice President, Financial Planning and Strategic Analysis from 2012 to 2014; Vice President, Chief Accounting Officer from 2008 to 2012; Controller and Chief Accounting Officer from 2008 to 2011 and Controller from 2005 to 2008. Prior to joining ViroPharma, Mr. Morris worked for KPMG LLP in its Healthcare Assurance practice. Mr. Morris received a B.S. in Accounting from Saint Joseph’s University and has been a CPA since 1999.
Eliseo Oreste Salinas, M.D. has served as our Chief Research and Development Officer since March 2021. Dr. Salinas served in various leadership roles at Acadia Pharmaceuticals, a biopharmaceutical company, including as Chief Scientific Officer, Senior Vice President, Head of External Innovation from August 2020 to March 2021 and Chief Scientific Officer, Senior Vice President, Head of Translational Research & External Innovation from September 2018 to August 2020. From June 2018 to September 2018, Dr. Salinas served as Chief Medical Officer for New World Laboratories. From August 2017 to May 2018, Dr. Salinas worked as a pharmaceutical consultant. From June 2015 to July 2017, Dr. Salinas served as President of Research & Development for Turing Pharmaceuticals, which included serving as Interim Chief Executive Officer from April 2017 to July 2017. Prior to that, Dr. Salinas served in various consulting and other leadership roles at Relmada Therapeutics, Stem Cells Inc., Elan Pharmaceuticals, Adolor Corporation, ViroChem Pharma Inc, Shire PLC, Wyeth Research, CR&D and Synthelabo Recherche. Dr. Salinas received an M.D. from the University of Buenos Aires, Argentina, completed his residency in Psychiatry at the Clinique des Maladies Mentales et de l'Encéphale, Paris, and obtained a Master of Science degree in Pharmacology from the Université Pierre et Marie Curie, Académie de Paris.California, Berkeley.
Gary Romano,Mark Forman, M.D., Ph.D.has served as our Chief Medical Officer since September 2019.July 2021. Dr. Forman is a neuropathologist and neuroscientist with deep expertise in development of drugs for neurological and psychiatric disorders. From January 2021 to July 2021, Dr. Forman led the Alzheimer’s Drug Discovery Foundation (ADDF) Scientific Affairs team that oversees their drug discovery and drug development portfolio. Prior to that,joining the ADDF, Dr. Romano workedForman was Vice President at Janssen Global Services, LLC, a pharmaceutical company,Acadia Pharmaceuticals from March 2019 to January 2021, where he served aswas Head of Development,
21
Alzheimer’s Disease / Neurology from May 2013pimavanserin for the treatment of hallucinations and delusions associated with dementia-related psychosis and trofinetide for Rett syndrome. Dr. Forman also spent 12 years at Merck where he was Executive Director and Neuroscience Lead in Translational Medicine, responsible for the neuroscience portfolio in early clinical development including contributions to September 2019the development of more than 20 novel therapeutics and as Head, Neurosciencemultiple New Drug Applications. Dr. Forman has been a member of scientific advisory board for Biomarkers from 2009 to 2013. Prior to Janssen, Dr. Romano served in various senior leadership roles at Johnson & Johnson, a healthcare company, and Merck & Co., Inc, a global biopharmaceutical company. Dr. Romano has held an adjunct clinical faculty position in the Department of NeurologyTreat FTD at the Lewis Katz School of MedicineAssociation for Frontotemporal Dementia since 2012. Dr. Forman received his Ph.D. at TempleRockefeller University, since January 2017. Dr. Romano receivedM.D. at Duke University and a B.S. in Biology from Trinity College, a Ph.D. in Molecular Neuroscience from Rockefeller University and an M.D. from Johns Hopkin’s School of Medicine, and he completed his post-graduate training in Neurology at the University of Pennsylvania.Yale University.
| 22 |
Alex Fotopoulos has served as our Chief Technical Officer since July 2019. From November 2017 to July 2019, Mr. Fotopoulos served as Senior Vice President, Technical Operations, Gene Therapy of Ultragenyx Pharmaceutical Inc., a biopharmaceutical company. From May 2016 to November 2017, Mr. Fotopoulos served as Senior Vice President, Technical Operations of Dimension Therapeutics, Inc., a biotechnology company, which was acquired by Ultragenyx Pharmaceutical Inc., focusing on the development of gene therapy for rare diseases associated with the liver and caused by genetic mutations. From August 2011 to May 2016, Mr. Fotopoulos served in various senior leadership roles at Momenta Pharmaceuticals, Inc., a biotechnology company, including Vice President, Technical Operations and Senior Director, Technical Operations. Prior to that, Mr. Fotopoulos served for 18 years in various senior leadership roles at Biogen, Inc., a biotechnology company, including Senior Director, Global Manufacturing Engineering and Director, Global Engineering Technology. Mr. Fotopoulos received a Diploma in Chemical Engineering at the National Technical University of Athens, Greece, a M.Sc. in Chemical Engineering from Tufts University, and a M.B.A. in General Management from the F.W. Olin Graduate School of Business at Babson College.
Edgar B. (Chip) CaleSimona King has served as our General CounselChief Financial Officer since August 2021. From September 2019 and Corporate Secretary since December 2019.2020 to June 2021, Ms. King served as Chief Financial Officer of Tmunity Therapeutics, a private biotherapeutics company. From June 1998 to July 2019 Mr. Caleto September 2020, she served in various senior leadership roles at GlaxoSmithKline plc, a multinational pharmaceutical company, including Senioras Vice President Legal Corporate Functions; Vice President, Associate General Counsel, Legal Operations, WWBD; Vice President, General Counsel, GSK Vaccines;of Financial Planning and Analysis and Assistant General Counsel. PriorTreasurer of Emergent BioSolutions. From September 2000 to that, Mr. Cale servedApril 2020, Ms. King worked at Bristol Myers Squibb, holding a number of finance roles of increasing responsibility across most functional aspects of the organization, including mergers and acquisitions, R&D, commercial and manufacturing, eventually leading the company’s global financial processes as Executive Director of Corporate Financial Planning and Analysis. Ms. King is a corporate and securities lawyer supporting emerging growth companies inCertified Public Accountant. She currently serves on the life science and technology industries at Venture Law Group LLP and Brobeck, Phleger & Harrison LLP. Mr. Cale received aglobal advisory board of the Healthcare Businesswomen’s Association (HBA). Ms. King earned her B.A. in Biologyeconomics at Kalamazoo College, and her M.B.A. in finance from Columbia Business School. She also has a diploma in African Studies from the University of Pennsylvania andCape Town, where she attended as a J.D. from the University of California, Berkeley.Rotary Ambassadorial Scholar.
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22
The following tables and accompanying narrative disclosure set forth information about the compensation provided to certain of our executive officers during the years ended December 31, 20192022 and 2020.2021. These executive officers, which consist of individuals who include ourserved as principal executive officer andofficers during the year ended December 31, 2022, our two most highly-compensated executive officers (other than our principal executive officer)officers) who were serving as executive officers at the end of the fiscal year ended December 31, 2020,2022, and the individual for whom disclosure would have been required but for the fact that such individual was not serving as an executive officer as of December 31, 2022, were:
| William Chou, M.D., our President and Chief Executive Officer; |
| · | Edgar B. (Chip) Cale, our General Counsel and former interim Chief Executive Officer; |
| · | Alex Fotopoulos, our Chief Technical Officer; |
| · | Simona King, our Chief Financial Officer; |
| · | Bruce Goldsmith, Ph.D., our former President and Chief Executive |
We refer to these individuals as our “named executive officers.”officers”.
| 24 |
Summary Compensation Table
The following table presents summary information regarding the total compensation for services rendered in all capacities that was awarded to and earned by our named executive officers during the years ended December 31, 20202022 and 2019:2021:
| Salary | Bonus | Non-Equity Incentive Plan Compensation | Option Awards | Restricted Stock Units | All Other Compensation | Total | ||||||||||||||||||||||||
| Name and principal position | Year | ($) | ($) | ($) (7) | ($) (8) | ($) (9) | ($) | ($) | ||||||||||||||||||||||
| William Chou, M.D. | 2022 | 111,538 | (1) | 200,000 | (6) | 72,000 | 900,663 | - | 11,887 | (10) | 1,296,088 | |||||||||||||||||||
| President and Chief Executive Officer | ||||||||||||||||||||||||||||||
| Edgar B. (Chip) Cale | 2022 | 508,125 | (2) | - | 149,351 | 682,911 | 66,500 | 16,882 | (11) | 1,423,769 | ||||||||||||||||||||
| General Counsel and Former Interim Chief Executive Officer | 2021 | 390,000 | - | 130,650 | 2,924,833 | - | 18,450 | (12) | 3,463,933 | |||||||||||||||||||||
| Alex Fotopoulos | 2022 | 463,479 | - | 176,878 | 914,648 | 66,500 | 13,611 | (13) | 1,635,117 | |||||||||||||||||||||
| Chief Technical Officer | 2021 | 413,750 | - | 151,019 | 1,796,934 | 741,000 | 18,664 | (14) | 3,121,367 | |||||||||||||||||||||
| Simona King | 2022 | 454,797 | - | 162,000 | 829,183 | 131,750 | 16,115 | (15) | 1,593,845 | |||||||||||||||||||||
| Chief Financial Officer | 2021 | 151,370 | (3) | - | 144,500 | 3,234,798 | - | 2,055 | (16) | 3,532,723 | ||||||||||||||||||||
| Bruce Goldsmith, Ph.D. | 2022 | 297,685 | (4) | - | - | 1,004,126 | - | 1,329,059 | (17) | 2,630,870 | ||||||||||||||||||||
Former President and Chief Executive Officer | 2021 | 550,000 | - | 242,000 | 4,480,759 | - | 15,625 | (18) | 5,288,384 | |||||||||||||||||||||
Monika (Maria) Toernsen | 2022 | 439,303 | - | - | 527,539 | - | 659,650 | (19) | 1,626,492 | |||||||||||||||||||||
| Former Chief Commercial Officer | 2021 | 192,123 | (5) | 50,000 | 144,500 | 2,027,525 | 260,800 | 4,548 | (20) | 2,679,496 | ||||||||||||||||||||
| | | | | | | | | | | | | | |
|
| |
| |
| |
| Non-equity |
| |
| |
| |
| | | | | | | | incentive plan | | Option | | All other | | |
| | | | | | Bonus | | compensation | | awards | | compensation | | Total |
Name and principal position | | Year | | Salary ($) | | ($) | | ($) (4) | | ($) (5) | | ($) | | ($) |
Bruce Goldsmith, Ph.D. |
| 2020 |
| 450,000 | (1) | — | | 258,750 |
| 15,985,702 |
| 12,623 | (6) | 16,707,075 |
Chief Executive Officer and President | | | | | | | | | | | | | | |
Stephen Squinto, Ph.D. |
| 2020 |
| 246,000 |
| — |
| — |
| 2,977,939 |
| 540,993 | (7) | 3,764,932 |
Former Interim Chief Executive Officer and former Acting Head of Research and Development |
| 2019 |
| 225,000 |
| — |
| 127,406 |
| 1,787,945 |
| — |
| 2,140,351 |
Jill Quigley |
| 2020 |
| 431,800 |
| — | | 202,950 |
| 3,390,497 |
| 362,922 | (8) | 4,388,169 |
Chief Operating Officer | | | | | | | | | | | | | | |
Gary Romano, M.D., Ph.D. |
| 2020 |
| 416,300 |
| 107,419 | (3) | 191,500 |
| 1,468,843 |
| 14,250 | (9) | 2,198,312 |
Chief Medical Officer |
| 2019 |
| 111,058 | (2) | — |
| 49,143 |
| 1,859,880 |
| 2,252 | (10) | 2,022,333 |
| 25 |
| 1) | Dr. |
| 2) | Mr. Cale’s salary reflects his base salary of $403,650 and includes additional compensation received for services provided as our Interim Chief Executive Officer in 2022. |
| 3) | Ms. King’s employment with us commenced on August 23, 2021. The salary reported reflects the pro rata portion of |
| 4) | Dr. |
| 5) | Ms. Toernsen’s employment with us commenced on |
| 6) | The amount reflects a |
| 7) | For additional information regarding the non-equity incentive plan compensation, see the section entitled "Non-Equity Incentive Plan Compensation." |
| 8) | Represents the grant date fair value of options awarded during the applicable year as computed in accordance with FASB ASC Topic 718. The assumptions used in calculating the grant date fair value of the stock options reported in the Options Award column are set forth in Note |
| 9) | Represents the grant date fair value of restricted stock units awarded during the applicable year as computed in accordance with FASB ASC Topic 718. The assumptions used in calculating the grant date fair value of the restricted stock units reported in the Restricted Stock Units column are set forth in Note 12 to our 2022 financial statements included with our 2022 Annual Report under Form 10-k. Note that the amounts reported in this column reflect the aggregate accounting cost, under generally accepted accounting principles, for these awards and do not necessarily correspond to the actual economic value that may be received by each named executive officer from the restricted stock units. |
| 10) | Represents a |
23
| 11) | Represents a |
| 12) | Represents a $14,500 matching contribution under our 401(k) Plan, $900 in cellphone allowances and $3,050 in discounts provided for purchases of the Company’s common stock under our 2020 Employee Stock Purchase Plan |
| 13) | Represents a $11,949 matching contribution under our 401(k) Plan, $830 in cellphone allowances and $832 in discounts provided for purchases of the Company’s common stock under our 2020 Employee Stock Purchase Plan |
| 14) | Represents a $13,817 matching contribution under our 401(k) Plan, $1,378 in cellphone allowances and $3,469 in discounts provided for purchases of the Company’s common stock under our 2020 Employee Stock Purchase Plan |
| 15) | Represents a $15,250 matching contribution under our 401(k) Plan, and |
| 16) | Represents a |
| 17) | Represents a |
| 18) | Represents a $14,500 matching contribution under our 401(k) Plan and $1,125 in cellphone allowances. |
| 19) | Represents $636,563 accrued in connection with the Toernsen Transition and Separation Agreement (as defined below) for salary, bonus, and COBRA premiums, $6,180 of compensation computed in accordance with FASB ASC Topic 718 for the extension of period to exercise for certain stock option awards, $15,250 matching contribution under our 401(k) Plan, $825 in cellphone allowances and $832 in discounts provided for purchases of the Company’s common stock under our 2020 Employee Stock Purchase Plan. |
| 20) | Represents a $3,923 matching contribution under our 401(k) Plan, and $625 in cellphone allowances. |
| 26 |
Non-Equity Incentive Plan Compensation
Annual bonuses for our executive officers are based on the achievement of individual performance objectives and corporate performance objectives.
Annual bonuses forobjectives established by our executive officersBoard of Directors that are based on the achievement ofgoals related to research and development, regulatory, financial and other general corporate and individual performance objectives.goals. The 20202022 target bonus amounts, expressed as a percentage of annual base salary, for our named executive officers were 45%55% for Dr. Chou, 40% for Mr. Cale, 40% for Mr. Fotopoulos, 40% for Ms. King, 55% for Dr. Goldsmith, and 40% for Ms. Quigley,Toernsen. In February 2023, based on the achievement of these corporate and 40% for Dr. Romano.personal performance objectives, our Board of Directors determined to award bonuses as reflected in the table above to our continuing officers.
2020
2022 Outstanding Equity Awards at Fiscal Year-End Table
The following table presents, for each of our named executive officers, information regarding outstanding stock options and restricted stock units held as of December 31, 2020.2022. Awards to date have been granted under our 2018 Equity Incentive Plan (2018 EIP), 2020 Equity Incentive Plan (2020 EIP) and 2021 Equity Inducement Plan (2021 EIP).
| | | | | | | | | | | | | | | | | | | |
| | Option Awards | |||||||||||||||||
| | | | | | Number of | | Number of | | | | | | | | | | | |
| | | | | | securities | | securities | | | | | | | | | | | |
| | | | | | underlying | | underlying | | Option | | | | | Number of | | | | |
| | | | Vesting | | unexercised | | unexercised | | exercise | | Option | | shares of stock | | Market value of | |||
| | Grant | | Commencement | | options | | options | | price | | expiration | | that have not | | shares that have | |||
Name |
| date |
| Date |
| exercisable |
| unexercisable |
| ($) |
| date |
| vested (#) |
| not vested ($) | |||
Bruce Goldsmith | | 1/28/2020 | (1) (3) | 1/28/2020 |
| 1,919,782 |
| — | | | 11.00 |
| | 1/28/2030 | | — | | | — |
Steve Squinto | | 2/6/2019 | (1)(4) | 9/19/2018 |
| — |
| — | | | 1.02 |
| | 2/6/2029 | | 112,815 | | | 2,884,680 |
| | 2/6/2019 | (1)(4) | 5/8/2019 |
| — |
| — | | | 1.02 |
| | 2/6/2029 | | 40,928 | | | 1,046,529 |
| | 10/23/2019 | (1) (5) | 10/9/2018 |
| 225,305 |
| — | | | 8.07 |
| | 10/23/2029 | | — | | | — |
| | 2/27/2020 | (2) (6) | 2/27/2020 |
| 185,776 |
| — | | | 18.00 |
| | 2/27/2030 | | — | | | — |
| | 2/27/2020 | (2) (7) | 3/27/2020 |
| 9,398 |
| 24,438.00 | | | 18.00 |
| | 2/27/2030 | | — | | | — |
Jill Quigley | | 2/6/2019 | (1) (8) | 11/12/2018 |
| 7,772 |
| 7,152.00 | | | 1.02 |
| | 2/6/2029 | | — | | | — |
| | 2/6/2019 | (1) (9) | 5/8/2019 |
| 40,542 |
| 47,888.00 | | | 1.02 |
| | 2/6/2029 | | — | | | — |
| | 2/6/2019 | (1) (10) | 2/6/2019 |
| — |
| — | |
| 1.02 |
| | 2/6/2029 | | 148,534 | | | 3,798,014 |
| | 1/15/2020 | (1) (11) | 12/17/2019 |
| 15,509 |
| 46,539.00 | | | 11.00 | |
| 1/15/2030 | | — | | | — |
| | 2/27/2020 | (2) (12) | 2/27/2020 |
| — |
| 211,001.00 | | | 18.00 | |
| 2/27/2030 | | — | | | — |
Gary Romano | | 10/23/2019 | (1)(13) | 8/20/2019 |
| 310,821 |
| — | | | 8.07 | |
| 10/23/2029 | | — | | | — |
| | 1/15/2020 | (1) (13) | 12/17/2019 |
| 54,850 |
| — | | | 11.00 | |
| 1/15/2030 | | — | | | — |
| | 2/27/2020 | (2) (14) | 2/27/2020 |
| — |
| 74,311.00 | | | 18.00 | |
| 2/27/2030 | | — | | | — |
| Option Awards | Stock Awards | ||||||||||||||||||||||||||||||
| Securities underlying | Securities underlying | Option | Number of shares or restricted | Market value of shares or restricted stock | |||||||||||||||||||||||||||
| Vesting | unexercised | unexercised | exercise | Option | stock units | units | |||||||||||||||||||||||||
| Grant | Equity | Commencement | options | options | price | expiration | Grant | that have not | that have | ||||||||||||||||||||||
| Name | date | Plan | date | exercisable | unexercisable | ($) | date | date | vested (#) | not vested ($) | |||||||||||||||||||||
| William Chou, M.D. | 10/10/2022 | 2020 EIP | (1) | 10/10/2022 | - | 219,500 | 1.32 | 10/10/2032 | |||||||||||||||||||||||
| 10/10/2022 | 2021 EIP | (1) | 10/10/2022 | - | 665,500 | 1.32 | 10/10/2032 | ||||||||||||||||||||||||
| Edgar B. (Chip) Cale | 10/23/2019 | 2018 EIP | (2) | 9/23/2019 | 274,254 | - | 8.07 | 10/22/2029 | |||||||||||||||||||||||
| 2/27/2020 | 2020 EIP | (3) | 2/27/2020 | 70,642 | 29,089 | 18.00 | 2/26/2030 | ||||||||||||||||||||||||
| 2/16/2021 | 2020 EIP | (4) | 2/15/2021 | 78,373 | 92,624 | 21.85 | 2/16/2031 | ||||||||||||||||||||||||
| 2/10/2022 | 2020 EIP | (5) | 2/10/2022 | 22,083 | 83,917 | 4.52 | 2/10/2032 | ||||||||||||||||||||||||
| 5/31/2022 | 2020 EIP | (6) | 5/31/2022 | 58,333 | 41,667 | 1.80 | 5/30/2032 | ||||||||||||||||||||||||
| 6/13/2022 | 2020 EIP | (7) | 6/13/2022 | 17,666 | 88,334 | 2.29 | 6/13/2032 | ||||||||||||||||||||||||
| 2020 EIP | 11/10/2022 | 50,000 | (18) | 69,000 | |||||||||||||||||||||||||||
| Alex Fotopoulos | 10/23/2019 | 2018 EIP | (8) | 7/22/2019 | 310,821 | - | 8.07 | 10/23/2029 | |||||||||||||||||||||||
| 1/15/2020 | 2018 EIP | (9) | 12/17/2019 | 54,850 | - | 10.99 | 1/15/2030 | ||||||||||||||||||||||||
| 2/27/2020 | 2020 EIP | (3) | 2/27/2020 | 52,636 | 21,675 | 18.00 | 2/26/2030 | ||||||||||||||||||||||||
| 2/16/2021 | 2020 EIP | (4) | 2/15/2021 | 48,125 | 56,875 | 21.85 | 2/16/2031 | ||||||||||||||||||||||||
| 2020 EIP | 5/17/2021 | 37,500 | (19) | 51,750 | |||||||||||||||||||||||||||
| 2/10/2022 | 2020 EIP | (5) | 2/10/2022 | 34,145 | 129,755 | 4.52 | 2/10/2032 | ||||||||||||||||||||||||
| 6/13/2022 | 2020 EIP | (7) | 6/13/2022 | 33,333 | 166,667 | 2.29 | 6/13/2032 | ||||||||||||||||||||||||
| 2020 EIP | 11/10/2022 | 50,000 | (18) | 69,000 | |||||||||||||||||||||||||||
| Simona King | 8/23/2021 | 2021 EIP | (10) | 8/23/2021 | 120,000 | 240,000 | 11.43 | 8/22/2031 | |||||||||||||||||||||||
| 2/10/2022 | 2020 EIP | (5) | 2/10/2022 | 33,125 | 125,875 | 4.52 | 2/11/2032 | ||||||||||||||||||||||||
| 2020 EIP | 4/18/2022 | 25,000 | (20) | 34,500 | |||||||||||||||||||||||||||
| 6/13/2022 | 2020 EIP | (7) | 6/13/2022 | 26,500 | 132,500 | 2.29 | 6/13/2032 | ||||||||||||||||||||||||
| 2020 EIP | 11/10/2022 | 50,000 | (18) | 69,000 | |||||||||||||||||||||||||||
| Bruce Goldsmith, Ph.D. | 1/28/2020 | 2018 EIP | (11) | 1/28/2020 | 1,919,782 | - | 10.99 | 9/1/2023 | |||||||||||||||||||||||
| 2/16/2021 | 2020 EIP | (12) | 2/16/2021 | 229,250 | - | 21.85 | 9/1/2023 | ||||||||||||||||||||||||
| 2/10/2022 | 2020 EIP | (13) | 2/10/2022 | 250,000 | - | 4.52 | 9/1/2032 | ||||||||||||||||||||||||
| 5/27/2022 | 2020 EIP | (14) | 5/27/2022 | 100,000 | - | 1.86 | 5/26/2032 | ||||||||||||||||||||||||
| Monika (Maria) Toernsen | 7/19/2021 | 2021 EIP | (15) | 7/19/2021 | 70,833 | - | 13.04 | 12/31/2023 | 7/19/2021 | 15,000 | (21) | 20,700 | |||||||||||||||||||
| 2/10/2022 | 2020 EIP | (16) | 2/10/2022 | 21,041 | - | 4.52 | 12/31/2023 | ||||||||||||||||||||||||
| 6/13/2022 | 2020 EIP | (17) | 6/13/2022 | 16,833 | - | 2.29 | 12/31/2023 | ||||||||||||||||||||||||
| 1) | The option vests as to 25% of the total shares on |
| 2) | The options vests as to 25% of the total shares on September 23, 2020 and then 2.0833% of the total shares vest monthly thereafter, with 100% of the total shares vested on September 23, 2023, subject to the reporting person’s provision of service to the Company on each vesting date. The option provides for an early-exercise provision and is exercisable as to unvested shares, subject to the |
24
| The option vests as to 25% of the total shares on February 27, 2021 and then 2.0833% of the total shares vest monthly thereafter, with 100% of the total shares vested on February 27, 2024, subject to the reporting person’s provision of service to the |
| 4) | The option |
| 5) | The option vests 2.0833% of the total shares on March 10, 2022, and then 2.0833% of the total shares vest monthly thereafter, with 100% of the total shares vested on February 10, 2026, subject to the reporting person’s provision of service to the Company on each vesting date. |
| 6) | The option vests 8.3333% of the total shares on June 30, 2022, and then 8.3333% of the total shares vest monthly thereafter, with 100% of the total shares vested on May 31, 2023, subject to the reporting person’s provision of service to the Company on each vesting date. The option was provided in connection with Mr. Cale’s appointment to interim Chief Executive Officer. |
| 7) | The option vests 2.7778% of the total shares on July 13, 2022, and then 2.7778% of the total shares vest monthly thereafter, with 100% of the total shares vested on June 13, 2025, subject to the reporting person’s provision of service to the Company on each vesting date. |
| 8) | The options vests as to 25% of the total shares on |
| 9) | The option vests as to 25% of the total shares on December 17, 2020 and then 2.0833% of the total shares vest monthly thereafter, with 100% of the total shares vested on December 17, 2023, subject to the reporting person’s provision of service to the |
| 10) | The |
| Under the original terms of the option |
| 12) | Under the original |
| 13) | Under the original terms of the option agreement, the option vested 2.0833% of the total shares on March 10, 2022, and then 2.0833% of the total shares vested monthly thereafter, with 100% of the total shares vested on February |
| 29 |
| 14) | The option was granted as part of |
| 15) | Under the original terms of the option agreement, the option vested as to 25% of the total shares on |
| 16) | Under the original terms of the option agreement, the option vested 2.0833% of the total shares, on March 10, 2022 and then 2.0833% of the total shares vested monthly thereafter, with 100% of the total shares vested on February 10, 2026. In connection with the Toernsen Transition and Separation Agreement, the deadline to exercise the unexercised vested shares was extended to December 31, 2023. |
| 17) | Under the original terms of the option agreement, the option vested 2.7778% of the total shares on July 13, 2022, and then 2.7778% of the total shares vested monthly thereafter, with 100% of the total shares vested on June 13, 2025. In connection with the Toernsen Transition and Separation Agreement, the deadline to exercise the unexercised vested shares was extended to December 31, 2023. |
| 18) | Represents restricted stock units, which 100% vests on December 31, 2023. |
| 19) | Represents restricted stock units, which 25% vests on June 15, 2022 and an additional 25% vesting |
| 20) | Represents restricted stock units, which 25% vests on April 18, 2023 and an additional 25% vesting annually thereafter, with 100% of the total shares vested on April 18, 2026. Mr. Fotopoulos vested in 12,500 restricted stock units during the year ended December 31, 2022. |
25
| 21) | Under the original terms of the restricted stock unit agreement, the restricted stock units 25% vested on September 15, 2022 and an additional 25% vesting annually thereafter, with 100% of the total shares vested on September 15, 2025. In connection with the Toernsen Transition and Separation Agreement, only the first 25% of her restricted stock units vested prior to December 31, 2022, and the remaining restricted stock units were forfeited. |
Employment Agreements
We have entered into employment agreements with certain senior management personnel, including our named executive officers. Each of these agreements provides for at-will employment and includes each officer’s base salary, a discretionary annual incentive bonus opportunity that may be based on individual and company performance and standard employee benefit plan participation. These agreements also provide for severance benefits upon termination of employment or a change in control of our company.
Dr. Squinto resigned from his position as our Interim Chief Executive Officer and President effective January 28, 2020 and was appointed Acting Head of Research and Development. Dr. Squinto resigned from our Board of Directors and as our Acting Head of Research and Development on February 18, 2021. We had entered into a consulting agreement with Dr. Squinto pursuant to which he received an annual fee at a rate of $309,000 per year through April 1, 2020, and $225,000 per year starting April 1, 2020, in each case payable quarterly in arrears. In addition, in the event of the earlier to occur of (i) Dr. Squinto’s continued service on our board through the second annual meeting of our stockholders held following the effective date of this registration statement and (ii) a change in control, each of Dr. Squinto’s then-outstanding unvested equity awards would accelerate and become fully vested upon such applicable event, subject to Dr. Squinto’s execution and non-revocation of a release of claims in our favor. Upon Dr. Squinto’s resignation from our Board of Directors and as our Acting Head of Research and Development, we accelerated vesting of Dr. Squinto’s outstanding stock options and restricted stock that were scheduled to accelerate on the date of our 2022 annual general meeting of stockholders and Dr. Squinto entered into a customary release of claims in our favor.
William Chou, M.D.
Effective January 28, 2020, Bruce Goldsmith, Ph.D.as of October 10, 2022, William Chou, M.D. was appointed as our Chief Executive Officer and President, and a member of our boardBoard of directors.Directors. Dr. Goldsmith will receive anChou’s employment agreement provides for at-will employment and included his initial base salary, discretionary annual salaryincentive bonus opportunity, certain initial equity incentive awards and standard employee benefit plan participation. The details of $500,000 and be eligible for an annual target bonus equal to 45% of his annual salary. In addition, Dr. Goldsmith was granted an option to purchase 1,919,782 shares, with 25% of the shares subject to the option vesting on January 28, 2021 and the remaining shares vesting in equal monthly installmentsChou’s compensation for the 36 months thereafter, so long as Dr. Goldsmith continues to provide services to us on each applicable vesting date.year ended 2022 is included above in the Summary Compensation Table.
Pursuant to the terms of his employment agreement, in the event Dr. GoldsmithChou is terminated without “cause” or resigns for “good reason” (as such terms are defined in his employment agreement), Dr. GoldsmithChou will, subject to his execution and non-revocation of a release of claims, be entitled to a lump-sum cash amount equal to (i) 12 months of his base salary, provided that such amount will be reduced to nine months’salary; (ii) 100% of his base salary if Dr. Goldsmith’s termination occurs prior to the completion of his first year of service on January 28, 2021; (ii) his annual target bonus for the year in which such termination occurs, pro-rated for a partial year of service;occurs; and (iii) the amount of COBRA premiums he would be required to pay to maintain group healthcare coverage as in effect on the date of his termination for 12 months. In addition, Dr. Goldsmith’s equity awards will accelerate and become exercisable, as applicable, with respect the number of shares that would have vested if Dr. Goldsmith had remained in service for an additional 24 months. Each of Dr. Goldsmith’s option awards, to the extent vested after giving effect to the foregoing sentence, will remain exercisable until the earliest to occur of the one-year anniversary following Dr. Goldsmith’s termination of service, and the original expiration date of such option.
| 30 |
In the event heDr. Chou is terminated without “cause” or resigns for “good reason” (as such terms are defined in his employment agreement), within two months prior to, or 12 months following, a “change in control” (as such term is defined in his employment agreement), then in lieu of the foregoing and subject to his execution and non-revocation of a release of claims, Dr. GoldsmithChou would be entitled to a lump-sum cash amount equal to (i)18 months of his base salary;salary at that time; (ii) 1.5x150% his annual target bonus for the year in which such termination occurs; and (iii) the amount of COBRA premiums he would be required to pay to maintain group healthcare coverage as in effect on the date of his termination for 18 months. In addition, in the event that a successor company does not assume or substitute equity awards held by Dr. GoldsmithChou in connection with a “change in control”, or Dr. GoldsmithChou experiences a qualifying termination as described above within two months prior to, or 12 months following a “change in control” (as defined in his employment agreement), Dr. Goldsmith’sChou's then-outstanding equity awards will become fully vested and exercisable, as applicable, and forfeiture restrictions thereon will lapse. Unless otherwise set forth in an applicable grant agreement, any performance conditions applicable to such equity awards will be deemed achieved at the greater of target or actual performance. Each of Dr. Goldsmith’s option awards, to the extent vested after giving effect to the foregoing sentence, will remain exercisable
26
until the earliest to occur of the one-year anniversary following Dr. Goldsmith’s termination of service, and the original expiration date of such option.
Each of the foregoing severance payments and benefits are subject to Dr. Goldsmith’sChou’s execution of a general release of claims against us, and his compliance with certain non-competition and non-solicitation provisions set forth in his employment agreement or our standard confidentiality and inventions assignment agreement. To the extent such severance payments and benefits are payable in connection with a change in control and would result in excise taxes imposed by Section 4999 of the Internal Revenue Code of 1986, as amended, then pursuant to this employment agreement, Dr. GoldsmithChou would be entitled to receive (i) the full payment of such payments and benefits or (ii) such lesser amount as would result in no portion of those payments and benefits being subject to the excise tax, whichever results in the greater net after-tax position for Dr. Goldsmith.Chou.
Edgar B. (Chip) Cale
On September 23, 2019, Edgar B. (Chip) Cale, was appointed as our General Counsel and Corporate Secretary. Effective as of the May 31, 2022, the Board also appointed Mr. Cale as Interim Chief Executive Officer and President, a role in which Mr. Cale served until October 10, 2022. Mr. Cale’s employment agreement provides for at-will employment and included his initial base salary, discretionary annual incentive bonus opportunity, certain initial equity incentive awards and standard employee benefit plan participation. The details of Mr. Cale’s compensation for the years ended 2022 and 2021 are included above in the Summary Compensation Table.
Pursuant to Ms. Quigley’sthe terms of his employment agreement, as amended, ifin the executive is terminated without “cause” or resigns for “good reason” (as such terms are defined in her employment agreement), she will be entitled to (i) a lump-sum payment equal to 12 months of her base salary, (ii) a taxable lump-sum payment equal to 12 months of COBRA premiums she would be required to pay to maintain group healthcare coverage as in effect on the date of termination, (iii) a pro-rata target bonus for the year in which the termination occurs and (iv) 12 months acceleration of any then-outstanding unvested equity awards.
Pursuant to Dr. Romano’s employment agreement, as amended, if prior to August 15, 2021, the executiveevent Mr. Cale is terminated without “cause” or resigns for “good reason” (as such terms are defined in his employment agreement), (i) heMr. Cale will, receive accelerated vestingsubject to his execution and non-revocation of stock options that are scheduleda release of claims, be entitled to vest in the 12 month period after his termination date, (ii) his post-termination exercise period for vested stock options as of August 15, 2021 will be extendeda lump-sum cash amount equal to 12 months after termination of employment, (iii) upon termination of employment, he will receive a lump sum payment equal to(i) 12 months of his annualbase salary plus a lump sum equal to twelve months(ii) the amount of the monthly COBRA premiumpremiums he would be required to pay to continuemaintain group healthcare coverage as in effect on the group health plan, payable within 30 days after the termination date and (iv) the terms of his non-competition agreement willtermination for 12 months.
In the event Mr. Cale is terminated without “cause” or resigns for “good reason” (as such terms are defined in his employment agreement), within two months prior to, or 12 months following, a “change in control”, then in lieu of the foregoing and subject to his execution and non-revocation of a release of claims, Mr. Cale would be revised.
entitled to a lump-sum cash amount equal to (i) 12 months of his base salary; (ii) 100% his annual target bonus for the year in which such termination occurs; and (iii) the amount of COBRA premiums he would be required to pay to maintain group healthcare coverage as in effect on the date of his termination for 12 months. In addition, in the event that a successor company does not assume or substitute the equity awards held by Ms. Quigley and Dr. RomanoMr. Cale in connection with a “change in control”, or if the executive is terminated without “cause” or resigns for “good reason”Mr. Cale experiences a qualifying termination as described above within two months prior to, or 12 months following a “change in control” (as such terms are defined in their respectivehis employment agreements)agreement), then, his or her then outstanding unvested options and otherMr. Cale's then-outstanding equity awards will become fully vested and exercisable, as applicable, and any forfeiture restrictions thereon will lapse and in addition to the severance noted above, and the executive will receive 100% of his or her then current target bonus, payable in a lump sum.lapse. Unless otherwise set forth in an applicable grant agreement, any performance conditions applicable to such equity awards will be deemed achieved at the greater of target or actual performance.
The
Each of the foregoing severance payments and benefits are subject to the Ms. Quigley’s and Dr. Romano’sMr. Cale’s execution of a general release of claims against us, and the executive’shis compliance with certain non-competition and non-solicitation provisions set forth in the executive’shis employment agreement or our standard confidentiality and inventions assignment agreement. To the extent such severance payments and benefits are payable in connection with a change in control and would result in excise taxes imposed by Section 4999 of the Internal Revenue Code of 1986, as amended, then pursuant to the executive’s respectivethis employment agreement, the executiveMr. Cale would be entitled to receive (i) the full payment of such payments and benefits or (ii) such lesser amount as would result in no portion of those payments and benefits being subject to the excise tax, whichever results in the greater net after-tax position for the executive.Mr. Cale.
| 31 |
27
Alexandros Fotopoulos
Effective as of ContentsJuly 22, 2019, Alexandros Fotopoulos was appointed as our Chief Technical Officer. Mr. Fotopoulos’ employment agreement provides for at-will employment and included his initial base salary, discretionary annual incentive bonus opportunity, certain initial equity incentive awards and standard employee benefit plan participation. The details of Mr. Fotopoulos’ compensation for the years ended 2022 and 2021 are included above in the Summary Compensation Table.
Pursuant to the terms of his employment agreement, in the event Mr. Fotopoulos is terminated without “cause” or resigns for “good reason” (as such terms are defined in his employment agreement), Mr. Fotopoulos will, subject to his execution and non-revocation of a release of claims, be entitled to a lump-sum cash amount equal to (i) 12 months of his base salary; (ii) the amount of COBRA premiums he would be required to pay to maintain group healthcare coverage as in effect on the date of his termination for 12 months.
In the event Mr. Fotopoulos is terminated without “cause” or resigns for “good reason” (as such terms are defined in his employment agreement), within two months prior to, or 12 months following, a “change in control”, then in lieu of the foregoing and subject to his execution and non-revocation of a release of claims, Mr. Fotopoulos would be entitled to a lump-sum cash amount equal to (i) 12 months of his base salary; (ii) 100% his annual target bonus for the year in which such termination occurs; and (iii) the amount of COBRA premiums he would be required to pay to maintain group healthcare coverage as in effect on the date of his termination for 12 months. In addition, in the event that a successor company does not assume or substitute equity awards held by Mr. Fotopoulos in connection with a “change in control”, or Mr. Fotopoulos experiences a qualifying termination as described above within two months prior to, or 12 months following a “change in control” (as defined in his employment agreement), Mr. Fotopoulos’ then-outstanding equity awards will become fully vested and exercisable, as applicable, and forfeiture restrictions thereon will lapse. Unless otherwise set forth in an applicable grant agreement, any performance conditions applicable to such equity awards will be deemed achieved at the greater of target or actual performance.
Each of the foregoing severance payments and benefits are subject to Mr. Fotopoulos’ execution of a general release of claims against us, and his compliance with certain non-competition and non-solicitation provisions set forth in his employment agreement or our standard confidentiality and inventions assignment agreement. To the extent such severance payments and benefits are payable in connection with a change in control and would result in excise taxes imposed by Section 4999 of the Internal Revenue Code of 1986, as amended, then pursuant to this employment agreement, Mr. Fotopoulos would be entitled to receive (i) the full payment of such payments and benefits or (ii) such lesser amount as would result in no portion of those payments and benefits being subject to the excise tax, whichever results in the greater net after-tax position for Mr. Fotopoulos.
Simona King
Effective as of August 23, 2021, Simona King, was appointed as our Chief Financial Officer. Ms. King’s employment agreement provides for at-will employment and included her initial base salary, discretionary annual incentive bonus opportunity, certain initial equity incentive awards and standard employee benefit plan participation. The details of Ms. King’s compensation for the years ended 2022 and 2021 are included above in the Summary Compensation Table.
Pursuant to the terms of her employment agreement, in the event Ms. King is terminated without “cause” or resigns for “good reason” (as such terms are defined in her employment agreement), Ms. King will, subject to her execution and non-revocation of a release of claims, be entitled to a lump-sum cash amount equal to (i) 12 months of her base salary; (ii) the amount of COBRA premiums she would be required to pay to maintain group healthcare coverage as in effect on the date of her termination for 12 months.
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In the event Ms. King is terminated without “cause” or resigns for “good reason” (as such terms are defined in her employment agreement), within two months prior to, or 12 months following, a “change in control”, then in lieu of the foregoing and subject to her execution and non-revocation of a release of claims, Ms. King will be entitled to a lump-sum cash amount equal to (i) 12 months of her base salary; (ii) 100% her annual target bonus for the year in which such termination occurs; and (iii) the amount of COBRA premiums she would be required to pay to maintain group healthcare coverage as in effect on the date of her termination for 12 months. In addition, in the event that a successor company does not assume or substitute equity awards held by Ms. King in connection with a “change in control”, or Ms. King experiences a qualifying termination as described above within two months prior to, or 12 months following a “change in control” (as defined in her employment agreement), Ms. King’s then-outstanding equity awards will become fully vested and exercisable, as applicable, and forfeiture restrictions thereon will lapse. Unless otherwise set forth in an applicable grant agreement, any performance conditions applicable to such equity awards will be deemed achieved at the greater of target or actual performance.
Each of the foregoing severance payments and benefits are subject to Ms. King’s execution of a general release of claims against us, and her compliance with certain non-competition and non-solicitation provisions set forth in her employment agreement or our standard confidentiality and inventions assignment agreement. To the extent such severance payments and benefits are payable in connection with a change in control and would result in excise taxes imposed by Section 4999 of the Internal Revenue Code of 1986, as amended, then pursuant to this employment agreement, Ms. King would be entitled to receive (i) the full payment of such payments and benefits or (ii) such lesser amount as would result in no portion of those payments and benefits being subject to the excise tax, whichever results in the greater net after-tax position for Ms. King.
Bruce Goldsmith, Ph.D.
Dr. Goldsmith’s separation from the Company was effective as of May 31, 2022. Pursuant to the terms of his Transition and Separation Agreement, dated May 27, 2022 (the “Goldsmith Transition and Separation Agreement), Dr. Goldsmith was provided (i) a lump sum payment of $566,500, equal to his annual salary for 2022; (ii) a lump-sum payment equal to $207,432, representing the pro rata portion of his 2022 target bonus; (iii) a lump sum of $31,135.25, which was equal to 12 months of the monthly COBRA premium required to pay to continue his group health coverage; and (iv) continued vesting in his then outstanding Company option awards through the Transition Term (as further defined below); and, (v) accelerated vesting of his then-unvested shares subject to his Company stock options were accelerated to the twenty-four (24) month anniversary of the last day of the Transition Term. In addition: (i) the deadline to exercise his unexercised vested shares subject to the Stock Option Agreement that was entered into with the Company on February 10, 2022 was extended to February 9, 2032; and (ii) the deadline to exercise the unexercised vested shares subject to the Stock Option Agreement that he entered into with the Company on January 28, 2020 and February 16, 2021 was extended to the twelve month anniversary of the last day of the Transition Term.
The Company engaged Dr. Goldsmith as a Board Advisor, with an effective date of May 31, 2022, until September 1, 2022 (the “Transition Term”). Pursuant to the terms of his Advisory agreement, dated May 27, 2022, Dr. Goldsmith was provided: (i) a monthly advisory fee equal to $50,000 through the Transition Term and (ii) an option (the “New Option”) to purchase 100,000 shares of common stock under the Company’s 2020 EIP at a strike price equal to the fair market value per share as determined by the Board on May 27, 2022, the date on which the Advisory Agreement was signed by both parties. The New Option became fully vested as of September 1, 2022 and the vested shares subject to the New Option shall be exercisable until May 26, 2032. In exchange for these termination benefits, Dr. Goldsmith executed a general release of claims against us and agreed to comply with certain non-competition and non-solicitation provisions set forth in the Separation Agreement and our standard confidentiality and inventions assignment agreement.
Monika (Maria) Toernsen
Ms. Toernsen’s separation from the Company was effective as of December 31st, 2022. Pursuant to the terms of her Transition and Separation Agreement, dated November 17, 2022 (the “Toernsen Transition and Separation Agreement), Ms. Toernsen was provided (i) a lump-sum payment equal to 12 months of her base salary in 2022; (ii) a lump-sum payment equal to $158,355, representing her target bonus for the 2022 calendar year after applying a 90% multiplier reflecting both Company and individual performance; (iii) a lump sum of $ 12,110, which was equal to 12 months of the monthly COBRA premium required to pay to continue her group health coverage; and (iv) the Company agreed to extend her post-employment deadline to exercise any unexercised vested options to purchase shares of the Company’s common stock to the twelve (12) month anniversary of December 31, 2022.
In exchange for these termination benefits, Ms. Toernsen executed a general release of claims against us and agreed to comply with certain non-competition and non-solicitation provisions set forth in her separation agreement and our standard confidentiality and inventions assignment agreement.
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EQUITY COMPENSATION PLAN INFORMATION
The following table presents information as of December 31, 20202022 with respect to compensation plans under which shares of our common stock may be issued.
| Plan category | Number of securities to be issued upon exercise of outstanding options, warrants and rights | Weighted- average exercise price of outstanding options, warrants and rights | Number of Securities to be issued upon vesting and settlement of outstanding restricted stock units | Number of securities remaining available for future issuance under equity compensation plans | ||||||||||||
| Equity compensation plans approved by security holders (1) | 9,800,557 | (1) | $ | 9.50 | 1,229,166 | 5,000,124 | (2) | |||||||||
| Equity compensation plans not approved by security holders (3) | 1,610,833 | (4) | 5.97 | 0 | 384,167 | (5) | ||||||||||
| Total | 11,411,390 | $ | 9.01 | 1,229,166 | 5,384,291 | |||||||||||
| | | | | | | |
|
| |
| Weighted- |
| | |
| | | | average | | | |
| | Number of securities | | exercise price of | | Number of securities | |
| | to be issued upon | | outstanding | | remaining available | |
| | exercise of | | options, | | for future issuance | |
| | outstanding options, |
| warrants and | | under equity | |
Plan category | | warrants and rights (1) |
| rights | | compensation plans (2) | |
Equity compensation plans approved by security holders |
| 6,928,111 | | $ | 12.36 |
| 3,320,729 |
Equity compensation plans not approved by security holders |
| — | |
| — |
| — |
Total |
| 6,928,111 | | $ | 12.36 |
| 3,320,729 |
| 1) | Includes outstanding awards under our 2018 |
| 2) | Represents (i) no shares available for future issuance under 2018 EIP, (ii) 3,880,210 shares available for issuance under our 2020 EIP, and (iii) 1,119,914 shares available for issuance under our 2020 ESPP. There are no shares of common stock available for issuance under our 2018 EIP, but the plan continues to govern the terms of stock options granted thereunder. Any shares of common stock that are subject to outstanding awards under the 2018 EIP that are issuable upon the exercise of stock options that expire or become unexercisable for any reason without having been exercised in full will generally be available for future grant and issuance under our 2020 EIP. In addition, the 2020 EIP provides for an automatic increase in the number of shares reserved for issuance thereunder on January 1 of each year for the remaining term of the plan equal to (a) 5.0% of the number of issued and outstanding shares of common stock on December 31 of the immediately preceding year, or (b) an amount as approved by the board each year. Pursuant to this provision, the number of shares reserved for grant and issuance under our 2020 Plan increased by |
| 3) | Includes outstanding awards under our 2021 EIP. |
| 4) | Reflects outstanding options under our 2021 EIP. |
| 5) | Reflects shares of common stock that remain available for grant under our 2021 EIP. |
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CERTAIN RELATIONSHIPS AND RELATED-PARTY TRANSACTIONS
Other than the executive officer and director compensation arrangements discussed above under the headings “Executive Compensation” and “Proposal No. 1—1 – Election of Directors-DirectorDirectors – Director Compensation,” respectively, below we describe the transactions to which we were a party since January 1, 2019,2021, in which the amount involved exceeded the lesser of $120,000 and 1% of the average of the Company’s total assets at year-end for the prior two completed fiscal years and in which our directors, executive officers, former directors, former executive officers, director nominees and holders of more than 5% of our common stock, or other persons as may be required to be disclosed pursuant to Item 404 of Regulation S-K, had a direct or indirect material interest.
Sales of Convertible Preferred Stock
Series A-2
In May 2019, we sold an aggregate of 22,209,301 shares of our Series A-2 convertible preferred stock at a purchase price of $2.15 per share for an aggregate purchase price of approximately $47.7 million. Each 4.43316 shares of our Series A-2 convertible preferred stock automatically converted into one share of our common stock upon completion of our initial public offering. The following table summarizes the Series A-2 convertible preferred stock purchased by our executive officers, members, or former members, of our board of directors or their affiliates and holders of more than 5% of our outstanding capital stock:
| | | | |
|
| Shares of |
| |
| | convertible | | Total |
|
| preferred |
| purchase |
Name of stockholder |
| stock | | price ($) |
Frazier Life Sciences IX, L.P.(1) |
| 4,651,163 |
| 10,000,000 |
OrbiMed Private Investment VII, LP(2) |
| 5,813,953 |
| 12,499,999 |
Versant Venture Capital VI, L.P.(3) |
| 4,651,163 |
| 10,000,000 |
New Leaf Ventures III, L.P.(4) |
| 2,325,581 |
| 4,999,999 |
Vivo Capital and affiliated entities(5) |
| 2,325,581 |
| 4,999,999 |
LAV Prescience Limited(6) |
| 2,325,581 |
| 4,999,999 |
Series B
In August 2019, we sold an aggregate of 33,592,907 shares of our Series B convertible preferred stock at a purchase price of $3.2745 per share for an aggregate purchase price of approximately $110.0 million. Each 4.43316 shares of our Series B convertible preferred stock automatically converted into one share of our common stock upon completion of our initial public offering. The following table summarizes the Series B convertible preferred stock purchased by our
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executive officers, members, or former members, of our board of directors or their affiliates and holders of more than 5% of our outstanding capital stock:
| | | | |
|
| Shares of |
| |
| | convertible | | Total |
|
| preferred |
| purchase |
Name of stockholder |
| stock | | price ($) |
Frazier Life Sciences IX, L.P.(1) |
| 1,918,681 |
| 6,282,721 |
OrbiMed and affiliated entities(2) |
| 5,452,252 |
| 17,853,498 |
Versant Vantage I, L.P.(3) |
| 3,140,241 |
| 10,282,719 |
New Leaf Ventures III, L.P.(4) |
| 959,340 |
| 3,141,359 |
Vivo Capital and affiliated entities(5) |
| 959,399 |
| 3,141,356 |
LAV Prescience Limited(6) |
| 1,791,528 |
| 5,866,358 |
AI Passage LLC(7) |
| 9,161,704 |
| 30,000,000 |
Insider Participation in Initial Public Offering
Certain of our principal stockholders and their affiliated entities, including stockholders affiliated with certain of our directors, purchased an aggregate of 3,233,900 shares of our common stock in our initial public offering on March 3, 2020 at the initial public offering price of $18.00 per share. The following table summarizes the shares of common stock purchased by our executive officers, members of our board of directors or their affiliates and holders of more than 5% of our outstanding capital stock in an amount exceeding $120,000:
| | | | |
|
| Shares of |
| Total purchase |
Name of stockholder | | stock | | price ($) |
Frazier Life Sciences IX, L.P.(1) |
| 550,000 |
| 9,900,000 |
OrbiMed and affiliated entities(2) |
| 700,000 |
| 12,600,000 |
Versant Ventures and affiliated entities(3) |
| 225,000 |
| 4,050,000 |
New Leaf Ventures and affiliated entities(4) |
| 250,000 |
| 4,500,000 |
Vivo Capital and affiliated entities(5) |
| 550,000 |
| 9,900,000 |
LAV Prescience Limited(6) |
| 400,000 |
| 7,200,000 |
AI Passage LLC(7) |
| 550,000 |
| 9,900,000 |
Athena Countouriotis |
| 8,900 |
| 160,200 |
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Consulting Agreement
In January 2019, we entered into a consulting agreement with James M. Wilson, M.D., Ph.D., an employee at the University of Pennsylvania, to serve as our Chief Scientific Advisor, and at the time of entry into the consulting agreement a holder of greater than 5% of our outstanding capital stock. We will make payments of $100,000 per year for such consulting services, payable in quarterly installments at the beginning of each fiscal quarter. Additionally, we granted to Dr. Wilson a stock option to purchase 137,774 shares of our common stock at an exercise price of $1.02 per share. The consulting agreement automatically renewed on December 31, 2019 for an additional calendar year and was amended in January 2020 to provide that upon a termination of Dr. Wilson’s service resulting from a notice of non-renewal of the term of his consulting agreement or a termination by us, in either case other than for cause (as defined in the consulting agreement), death or disability within 2 months prior to, or 12 months following a change in control, then subject to Dr. Wilson’s execution and non-revocation of a release of claims in our favor, each of Dr. Wilson’s then-outstanding equity awards will accelerate and become fully vested upon such termination of service provided that, any equity awards subject to performance-based vesting conditions may be subject to alternative treatment pursuant to the applicable grant agreement and, absent any such treatment in the grant agreement, the vesting acceleration will be deemed achieved at the greater of target or actual performance.
Relationships with an Immediate Family Member of our Former Chief Operating Officer
In November 2018, we entered into a consulting agreement with Chris Quigley, the spouse of Jill Quigley, our former Chief Operating Officer, to provide financial consulting services. In accordance with this agreement as compensation for services provided, we paid Mr. Quigley approximately $121,000 in 2019. In January 2020, we hired Mr. Quigley as Senior Director of Finance. HeIn 2020, he received a new hire option grant to purchase 36,56736,566 shares of common stock at an exercise price of $11.00 and his$11.00. In 2021, he received an annual employee option grant to purchase 10,500 shares of common stock at an exercise price of $21.85. His annual base salary isfor both 2020 and 2021 was less than $225,000, consistent with the compensation paid to employees in similar positions. On January 3, 2022, Mr. Quigley terminated his employment with the Company.
University of Pennsylvania
We are party to a license, research and collaboration agreement with Penn’s GTP, headed by Dr. Wilson. In accordance with this agreement we issued shares to Penn that caused them to become a holder of more than 5% of our outstanding common stock. Under our agreement with Penn we provide certain funding to Penn to conduct research and discovery work.
Loans to Executive Officers
In February 2019, we received a promissory note from Jill M. Quigley, J.D., our Chief Operating Officer, in connection with Ms. Quigley’s purchase of shares of our common stock. The principal amount of the note was $0.3 million, which accrued interest at 2.91%, compounding annually. The note was forgiven in full in January 2020.
In February 2019, we received a promissory note from Stephen Squinto, Ph.D., our former interim Chief Executive Officer, former Acting Head of Research and Development and a former director, in connection with Dr. Squinto’s
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purchase of shares of our common stock. The principal amount of the note was $0.6 million, which accrued interest at 2.91%, compounding annually. The note was forgiven in full in January 2020.
Policies and Procedures for Related-Party Transactions
Our Board of Directors has adopted a written related person transactions policy. Under this policy, our executive officers, directors, nominees for election as a director, beneficial owners of more than 5% of our common stock, and any members of the immediate family of and any entity affiliated with any of the foregoing persons, are not permitted to enter into a material related person transaction with us without the review and approval of our audit committee,Audit Committee, or a committee composed solely of independent directors in the event it is inappropriate for our audit committeeAudit Committee to review such transaction due to a conflict of interest. The policy provides that any request for us to enter into a transaction with an executive officer, director, nominee for election as a director, beneficial owner of more than 5% of our common stock or with any of their immediate family members or affiliates in which the amount involved exceeds $120,000 will be presented to our audit committeeAudit Committee for review, consideration and approval. In approving or rejecting any such proposal, our audit committeeAudit Committee will consider the relevant facts and circumstances available and deemed relevant to the audit committee,Audit Committee, including, but not limited to, whether the transaction is on terms no less favorable than terms generally available to an unaffiliated third party under the same or similar circumstances and the extent of the related person’s interest in the transaction.
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Stockholder Proposals to be Presented at Next Annual Meeting
Requirements for Stockholder Proposals to be Brought Before an Annual Meeting. Our bylaws
The Bylaws provide that for stockholder nominations to our Board of Directors or other proposals to be considered at an annual meeting of stockholders, the stockholder must give timely notice thereof in writing to the Corporate Secretary at Passage Bio, Inc., One Commerce Square, 2005 Market Street, 39th Floor, Philadelphia, Pennsylvania 19103.19103.
To be timely for our company’s annual meeting of stockholders to be held in 2022 (20222024 (2024 Annual Meeting), a stockholder’s notice must be delivered to or mailed and received by our Corporate Secretary at our principal executive offices not earlier than the close of business5:00 p.m. Eastern Time on January 27, 202225, 2024 and not later than the close of business5:00 p.m. Eastern Time on February 26, 2022.25, 2024. A stockholder’s notice to the Corporate Secretary must set forth as to each matter the stockholder proposes to bring before the 20222024 Annual Meeting the information required by applicable law and our bylaws.the Bylaws. However, if the date of the 20222024 Annual Meeting is more than 30 days before or more than 70 days after the one-year anniversary of the date of our 20212023 Annual Meeting, for the stockholder notice to be timely, it must be delivered to the Corporate Secretary at our principal executive offices not earlier than the close of business on the 120th day prior to the currently proposed annual meeting and not later than the close of business on the later of (1) the 90th day prior to such annual meeting or (2) the close of business on the 10th day following the day on which public announcement of the date of such meeting is first made by us.
Requirements for Stockholder Proposals to be Considered for Inclusion in our Proxy Materials.
Stockholder proposals submitted pursuant to Rule 14a-8 under the Exchange Act and intended to be presented at our 20222024 Annual Meeting must be received by us not later than January 14, 2022December 16, 2023 in order to be considered for inclusion in our proxy materials for that meeting. A stockholder’s notice to the Corporate Secretary must set forth as to each matter the stockholder proposes to bring before the 20222024 Annual Meeting the information required by applicable law and our bylaws.the Bylaws.
Available Information
The Annual Report on Form 10-K is also available at https://investors.passagebio.com/financials-and-filings/sec-filings.sec-filings.
“Householding” – Stockholders Sharing the Same Address
The SEC has adopted rules that permit companies and intermediaries (such as brokers) to implement a delivery procedure called “householding.” Under this procedure, multiple stockholders who reside at the same address may receive a single copy of our Annual Report on Form 10-K and proxy materials, including the Notice of Internet Availability, unless the affected stockholder has provided other instructions. This procedure reduces printing costs and postage fees, and helps protect the environment as well.
We expect that a number of brokers with account holders who are our stockholders will be “householding” our Annual Report on Form 10-K and proxy materials, including the Notice of Internet Availability. A single Notice of internet Availability and, if applicable, a single set of Annual Report on Form 10-K and other proxy materials will be delivered to multiple stockholders sharing an address unless contrary instructions have been received from one or more of the affected stockholders. Once you have received notice from your broker that it will be “householding” communications to your address, “householding” will continue until you are notified otherwise or until you revoke your consent. Stockholders may revoke their consent at any time by contacting their broker.
Upon written or oral request, we will undertake to promptly deliver a separate copy of the Notice of Internet Availability and, if applicable, proxy statement, proxy card, Annual Report on Form 10-K and other proxy materials to any stockholder at a shared address to which a single copy of any of those documents was delivered. To receive a separate copy of the Notice of Internet Availability and, if applicable, proxy statement, proxy card, Annual Report on Form 10-K and other proxy materials, you may write our Corporate Secretary at Passage Bio, Inc., One Commerce Square, 2005 Market Street, 39th Floor, Philadelphia, Pennsylvania 19103, Attn: Corporate Secretary, submit a request on our website at https://investors.passagebio.com/investor-resources/investor-contact or contact Edgar Cale at (267) 866-0311.
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Any stockholders who share the same address and currently receive multiple copies of our Notice of Internet Availability or Annual Report on Form 10-K and other proxy materials who wish to receive only one copy in the future can contact their bank, broker or other holder of record to request information about “householding” or our Investor Relations Department at the address or telephone number listed above.
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Our Board of Directors does not presently intend to bring any other business before the Annual Meeting and, so far as is known to the Board of Directors, no matters are to be brought before the Annual Meeting except as specified in the notice of the Annual Meeting. As to any business that may arise and properly come before the Annual Meeting, however, it is intended that proxies, in the form enclosed, will be voted in respect thereof in accordance with the judgment of the persons voting such proxies.
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Proposed Amended and Restated Certificate of Incorporation
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PASSAGE BIO, INC.
RESTATED CERTIFICATE OF INCORPORATION
Passage BIO, Inc., a Delaware corporation, hereby certifies as follows:
1. The name of the corporation is “Passage BIO, Inc.” The date of the filing of its original Certificate of Incorporation with the Secretary of State was July 26, 2017.
2. The Restated Certificate of Incorporation of the corporation attached hereto as Exhibit “A”, which is incorporated herein by this reference, and which restates, integrates and further amends the provisions of the Certificate of Incorporation of this corporation as previously amended and/or restated, has been duly adopted by this corporation’s Board of Directors and by the stockholders in accordance with Sections 242 and 245 of the General Corporation Law of the State of Delaware, with the approval of the corporation’s stockholders having been given by written consent without a meeting in accordance with Section 228 of the General Corporation Law of the State of Delaware.
IN WITNESS WHEREOF, this corporation has caused this Restated Certificate of Incorporation to be signed by its duly authorized officer and the foregoing facts stated herein are true and correct.
| Dated: [ ], 2023 | PASSAGE BIO, INC. | |
| By: | /s/ William Chou, M.D. | |
| Name: William Chou, M.D. | ||
| Title: President and Chief Executive Officer | ||
EXHIBIT “A”
PASSAGE BIO, INC.
RESTATED CERTIFICATE OF INCORPORATION
Article I: NAME
The name of the corporation is Passage BIO, Inc. (the “Corporation”).
Article II: AGENT FOR SERVICE OF PROCESS
The address of the Corporation’s registered office in the State of Delaware is 1209 North Orange Street, Wilmington, Delaware 19801 in the County of New Castle. The name of the registered agent of the Corporation at that address is The Corporation Trust Company.
Article III: PURPOSE
The purpose of the Corporation is to engage in any lawful act or activity for which corporations may be organized under the General Corporation Law of the State of Delaware (the “General Corporation Law”).
Article IV: AUTHORIZED STOCK
1. Total Authorized. The total number of shares of all classes of stock that the Corporation has authority to issue is 310,000,000 shares, consisting of two classes: 300,000,000 shares of Common Stock, $0.0001 par value per share (“Common Stock”), and 10,000,000 shares of Preferred Stock, $0.0001 par value per share (“Preferred Stock”).
2. Designation of Additional Series.
2.1 The Board of Directors of the Corporation (the “Board”) is authorized, subject to any limitations prescribed by the law of the State of Delaware, to provide for the issuance of the shares of Preferred Stock in one or more series, and, by filing a Certificate of Designation pursuant to the applicable law of the State of Delaware (“Certificate of Designation”), to establish from time to time the number of shares to be included in each such series, to fix the designation, powers (including voting powers), preferences and relative, participating, optional or other special rights, if any, of the shares of each such series and any qualifications, limitations or restrictions thereof, and, except where otherwise provided in the applicable Certificate of Designation, to thereafter increase (but not above the total number of authorized shares of the Preferred Stock) or decrease (but not below the number of shares of such series then outstanding) the number of shares of any such series. The number of authorized shares of Preferred Stock may also be increased or decreased (but not below the number of shares thereof then outstanding) by the affirmative vote of the holders of two-thirds of the voting power of all of the then-outstanding shares of capital stock of the Corporation entitled to vote thereon, without a separate vote of the holders of the Preferred Stock, irrespective of the provisions of Section 242(b)(2) of the General Corporation Law, unless a separate vote of the holders of one or more series is required pursuant to the terms of any Certificate of Designation; provided, however, that if two-thirds of the Whole Board (as defined below) has approved such increase or decrease of the number of authorized shares of Preferred Stock, then only the affirmative vote of the holders of a majority of the voting power of all of the then-outstanding shares of the capital stock of the Corporation entitled to vote generally in the election of directors, voting together as a single class, without a separate vote of the holders of the Preferred Stock (unless a separate vote of the holders of one or more series is required pursuant to the terms of any Certificate of Designation), shall be required to effect such increase or decrease. For purposes of this Restated Certificate of Incorporation (as the same may be amended and/or restated from time to time, including pursuant the terms of any Certificate of Designation designating a series of Preferred Stock, this “Certificate of Incorporation”), the term “Whole Board” shall mean the total number of authorized directors whether or not there exist any vacancies in previously authorized directorships.
2.2 Except as otherwise expressly provided in any Certificate of Designation designating any series of Preferred Stock pursuant to the foregoing provisions of this Article IV, any new series of Preferred Stock may be designated, fixed and determined as provided herein by the Board without approval of the holders of Common Stock or the holders of Preferred Stock, or any series thereof, and any such new series may have powers, preferences and rights, including, without limitation, voting powers, dividend rights, liquidation rights, redemption rights and conversion rights, senior to, junior to or pari passu with the rights of the Common Stock, any series of Preferred Stock or any future class or series of capital stock of the Corporation.
2.3 Each outstanding share of Common Stock shall entitle the holder thereof to one vote on each matter properly submitted to the stockholders of the Corporation for their vote; provided, however, that, except as otherwise required by law, holders of Common Stock shall not be entitled to vote on any amendment to this Certificate of Incorporation that relates solely to the terms of one or more outstanding series of Preferred Stock if the holders of such affected series are entitled, either separately or together as a class with the holders of one or more other such series, to vote thereon pursuant to this Certificate of Incorporation.
Article V: AMENDMENT OF BYLAWS
The Board shall have the power to adopt, amend or repeal the Bylaws of the Corporation (as the same may be amended and/or restated from time to time, the “Bylaws”). Any adoption, amendment or repeal of the Bylaws by the Board shall require the approval of a majority of the Whole Board. The stockholders shall also have power to adopt, amend or repeal the Bylaws; provided, however, that notwithstanding any other provision of this Certificate of Incorporation or any provision of law that might otherwise permit a lesser or no vote, but in addition to any vote of the holders of any class or series of stock of the Corporation required by applicable law or by this Certificate of Incorporation, the affirmative vote of the holders of at least two-thirds of the voting power of all of the then-outstanding shares of the capital stock of the Corporation entitled to vote generally in the election of directors, voting together as a single class, shall be required for the stockholders to adopt, amend or repeal any provision of the Bylaws; provided further, that, in the case of any proposed adoption, amendment or repeal of any provisions of the Bylaws that is approved by the Board and submitted to the stockholders for adoption thereby, if two-thirds of the Whole Board has approved such adoption, amendment or repeal of any provisions of the Bylaws, then only the affirmative vote of the holders of a majority of the voting power of all of the then-outstanding shares of the capital stock of the Corporation entitled to vote generally in the election of directors, voting together as a single class, shall be required to adopt, amend or repeal any provision of the Bylaws.
Article VI: MATTERS RELATING TO THE BOARD OF DIRECTORS
1. Director Powers. Except as otherwise provided by the General Corporation Law or this Certificate of Incorporation, the business and affairs of the Corporation shall be managed by or under the direction of the Board.
2. Number of Directors. Subject to the special rights of the holders of any series of Preferred Stock to elect additional directors under specified circumstances, the total number of directors constituting the Whole Board shall be fixed from time to time exclusively by resolution adopted by a majority of the Whole Board.
3. Classified Board. Subject to the special rights of the holders of one or more series of Preferred Stock to elect additional directors under specified circumstances, the directors shall be divided, with respect to the time for which they severally hold office, into three classes designated as Class I, Class II and Class III, respectively (the “Classified Board”). The Board may assign members of the Board already in office to the Classified Board. The number of directors in each class shall be as nearly equal as is practicable. At each annual meeting of stockholders, directors elected to succeed those directors of the class whose terms then expire shall be elected for a term of office expiring at the third succeeding annual meeting of stockholders after their election.
4. Term and Removal. Each director shall hold office until the annual meeting at which such director’s term expires and until such director’s successor is duly elected and qualified, or until such director’s earlier death, resignation, disqualification or removal. Any director may resign by delivering a resignation in writing or by electronic transmission to the Corporation at its principal office or to the Chairperson of the Board, the Chief Executive Officer, or the Secretary. Subject to the special rights of the holders of any series of Preferred Stock, no director may be removed from the Board except for cause and only by the affirmative vote of the holders of at least two-thirds of the voting power of the then-outstanding shares of capital stock of the Corporation entitled to vote thereon, voting together as a single class. In the event of any increase or decrease in the authorized number of directors, (a) each director then serving as such shall nevertheless continue as a director of the class of which he or she is a member and (b) the newly created or eliminated directorships resulting from such increase or decrease shall be apportioned by the Board among the classes of directors so as to make all classes as nearly equal in number as is practicable, provided that no decrease in the number of directors constituting the Board shall shorten the term of any director.
5. Board Vacancies and Newly Created Directorships. Subject to the special rights of the holders of any series of Preferred Stock, any vacancy occurring in the Board for any cause, and any newly created directorship resulting from any increase in the authorized number of directors, shall be filled only by the affirmative vote of a majority of the directors then in office, even if less than a quorum, or by a sole remaining director, and shall not be filled by the stockholders. Any director elected in accordance with the preceding sentence shall hold office for a term expiring at the annual meeting of stockholders at which the term of office of the class to which the director has been assigned expires and until such director’s successor shall have been duly elected and qualified, or until such director’s earlier death, resignation, disqualification or removal.
6. Vote by Ballot. Election of directors need not be by written ballot unless the Bylaws shall so provide.
7. Preferred Directors. If and for so long as the holders of any series of Preferred Stock have the special right to elect additional directors, then upon commencement and for the duration of the period during which such right continues: (i) the then otherwise total authorized number of directors of the Corporation shall automatically be increased by such specified number of directors, and the holders of such Preferred Stock shall be entitled to elect the additional directors so provided for or fixed pursuant to said provisions, and (ii) each such additional director shall serve until such director’s successor shall have been duly elected and qualified, or until such director’s right to hold such office terminates pursuant to said provisions, whichever occurs earlier, subject to his or her earlier death, resignation, retirement, disqualification or removal. Except as otherwise provided by the Board in the resolution or resolutions establishing such series, whenever the holders of any series of Preferred Stock having such right to elect additional directors are divested of such right pursuant to the provisions of such stock, the terms of office of all such additional directors elected by the holders of such stock, or elected to fill any vacancies resulting from the death, resignation, disqualification or removal of such additional directors, shall forthwith terminate and the total authorized number of directors of the Corporation shall be reduced accordingly.
Article VII: DIRECTOR AND OFFICER LIABILITY
1. Limitation of Liability. To the fullest extent permitted by law, neither a director of the Corporation nor an officer of the Corporation shall be personally liable for monetary damages for breach of fiduciary duty as a director or officer, as applicable. Without limiting the effect of the preceding sentence, if the General Corporation Law is hereafter amended to authorize the further elimination or limitation of the liability of a director or officer, then the liability of a director of the Corporation or officer of the Corporation shall be eliminated or limited to the fullest extent permitted by the General Corporation Law, as so amended.
2. Change in Rights. Neither any amendment nor repeal of this Article VII, nor the adoption of any provision of this Certificate of Incorporation inconsistent with this Article VII, shall eliminate, reduce or otherwise adversely affect any limitation on the personal liability of a director of the Corporation or officer of the Corporation existing at the time of such amendment, repeal or adoption of such an inconsistent provision.
Article VIII: MATTERS RELATING TO STOCKHOLDERS
1. No Action by Written Consent of Stockholders. Subject to the rights of any series of Preferred Stock then outstanding, no action shall be taken by the stockholders of the Corporation except at a duly called annual or special meeting of stockholders and no action shall be taken by the stockholders of the Corporation by written consent in lieu of a meeting.
2. Special Meeting of Stockholders. Special meetings of the stockholders of the Corporation may be called only by the Chairperson of the Board, the Chief Executive Officer, the Lead Independent Director (as defined in the Bylaws), the President, or the Board acting pursuant to a resolution adopted by a majority of the Whole Board and may not be called by the stockholders or any other person or persons.
3. Advance Notice of Stockholder Nominations and Business Transacted at Special Meetings. Advance notice of stockholder nominations for the election of directors of the Corporation and of business to be brought by stockholders before any meeting of stockholders of the Corporation shall be given in the manner provided in the Bylaws. Business transacted at special meetings of stockholders shall be limited to the purpose or purposes stated in the notice of meeting.
Article IX: CHOICE OF FORUM
Unless the Corporation consents in writing to the selection of an alternative forum, the Court of Chancery of the State of Delaware, to the fullest extent permitted by law, shall be the sole and exclusive forum for: (a) any derivative action or proceeding brought on behalf of the Corporation; (b) any action asserting a claim of breach of a fiduciary duty owed by, or other wrongdoing by, any director, officer, stockholder, employee or agent of the Corporation to the Corporation or the Corporation’s stockholders; (c) any action asserting a claim against the Corporation arising pursuant to any provision of the General Corporation Law, this Certificate of Incorporation or the Bylaws or as to which the General Corporation Law confers jurisdiction on the Court of Chancery of the State of Delaware; (d) any action to interpret, apply, enforce or determine the validity of this Certificate of Incorporation or the Bylaws; or (e) any action asserting a claim against the Corporation governed by the internal affairs doctrine.
Any person or entity purchasing or otherwise acquiring or holding any interest in shares of capital stock of the Corporation shall be deemed to have notice of and to have consented to the provisions of this Article IX.
Article X: AMENDMENT OF CERTIFICATE OF INCORPORATION
If any provision of this Certificate of Incorporation shall be held to be invalid, illegal, or unenforceable, then such provision shall nonetheless be enforced to the maximum extent possible consistent with such holding and the remaining provisions of this Certificate of Incorporation (including without limitation, all portions of any section of this Certificate of Incorporation containing any such provision held to be invalid, illegal, or unenforceable, which is not invalid, illegal, or unenforceable) shall remain in full force and effect.
The Corporation reserves the right to amend or repeal any provision contained in this Certificate of Incorporation in the manner prescribed by the laws of the State of Delaware and all rights conferred upon stockholders are granted subject to this reservation; provided, however, that, notwithstanding any provision of this Certificate of Incorporation or any provision of law that might otherwise permit a lesser vote or no vote (but subject to Section 2 of Article IV hereof), but in addition to any vote of the holders of any class or series of the stock of the Corporation required by law or by this Certificate of Incorporation, the affirmative vote of the holders of at least two-thirds of the voting power of all of the then-outstanding shares of the capital stock of the Corporation entitled to vote generally in the election of directors, voting together as a single class, shall be required to amend or repeal any provision of this Certificate of Incorporation; provided, further, that if two-thirds of the Whole Board has approved such amendment or repeal of any provisions of this Certificate of Incorporation, then only the affirmative vote of the holders of at least a majority of the voting power of all of the then-outstanding shares of capital stock of the Corporation entitled to vote generally in the election of directors, voting together as a single class (in addition to any other vote of the holders of any class or series of stock of the Corporation required by law of by this Certificate of Incorporation), shall be required to amend or repeal such provisions of this Certificate of Incorporation.
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